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用于药妆品的海洋鱼类蛋白质和肽：综述

Marine Fish Proteins and Peptides for Cosmeceuticals: A Review.

作者信息

Venkatesan Jayachandran, Anil Sukumaran, Kim Se-Kwon, Shim Min Suk

机构信息

Division of Bioengineering, Incheon National University, Incheon 406-772, Korea.

Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin Abdulaziz University, Riyadh, Post Box 153, AIKharj 11942, Saudi Arabia.

出版信息

Mar Drugs. 2017 May 18;15(5):143. doi: 10.3390/md15050143.

DOI:10.3390/md15050143
PMID:28524092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5450549/
Abstract

Marine fish provide a rich source of bioactive compounds such as proteins and peptides. The bioactive proteins and peptides derived from marine fish have gained enormous interest in nutraceutical, pharmaceutical, and cosmeceutical industries due to their broad spectrum of bioactivities, including antioxidant, antimicrobial, and anti-aging activities. Recently, the development of cosmeceuticals using marine fish-derived proteins and peptides obtained from chemical or enzymatical hydrolysis of fish processing by-products has increased rapidly owing to their activities in antioxidation and tissue regeneration. Marine fish-derived collagen has been utilized for the development of cosmeceutical products due to its abilities in skin repair and tissue regeneration. Marine fish-derived peptides have also been utilized for various cosmeceutical applications due to their antioxidant, antimicrobial, and matrix metalloproteinase inhibitory activities. In addition, marine fish-derived proteins and hydrolysates demonstrated efficient anti-photoaging activity. The present review highlights and presents an overview of the current status of the isolation and applications of marine fish-derived proteins and peptides. This review also demonstrates that marine fish-derived proteins and peptides have high potential for biocompatible and effective cosmeceuticals.

摘要

海洋鱼类是蛋白质和肽等生物活性化合物的丰富来源。源自海洋鱼类的生物活性蛋白质和肽因其广泛的生物活性，包括抗氧化、抗菌和抗衰老活性，在营养保健品、制药和药妆品行业引起了极大的关注。最近，利用从鱼类加工副产物的化学或酶水解中获得的海洋鱼类衍生蛋白质和肽开发药妆品的情况迅速增加，这归因于它们在抗氧化和组织再生方面的活性。海洋鱼类衍生的胶原蛋白因其在皮肤修复和组织再生方面的能力而被用于药妆产品的开发。海洋鱼类衍生的肽也因其抗氧化、抗菌和基质金属蛋白酶抑制活性而被用于各种药妆应用。此外，海洋鱼类衍生的蛋白质和水解产物表现出有效的抗光老化活性。本综述重点介绍并概述了海洋鱼类衍生蛋白质和肽的分离及应用现状。本综述还表明，海洋鱼类衍生的蛋白质和肽在生物相容性和有效的药妆品方面具有很高的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/7cc5deecf2bd/marinedrugs-15-00143-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/3031f1599550/marinedrugs-15-00143-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/a071b02da52e/marinedrugs-15-00143-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/ac78c84f4ded/marinedrugs-15-00143-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/f25f3fca2377/marinedrugs-15-00143-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/7cc5deecf2bd/marinedrugs-15-00143-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/3031f1599550/marinedrugs-15-00143-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/a071b02da52e/marinedrugs-15-00143-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/ac78c84f4ded/marinedrugs-15-00143-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/f25f3fca2377/marinedrugs-15-00143-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7946/5450549/7cc5deecf2bd/marinedrugs-15-00143-g005.jpg

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