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碳纳米管作为抗菌剂。

Carbon nanotubes as anti-bacterial agents.

作者信息

Mocan Teodora, Matea Cristian T, Pop Teodora, Mosteanu Ofelia, Buzoianu Anca Dana, Suciu Soimita, Puia Cosmin, Zdrehus Claudiu, Iancu Cornel, Mocan Lucian

机构信息

Department of Nanomedicine, "Octavian Fodor" Gastroenterology Institute, 19-21 Croitorilor Street, Cluj-Napoca, Romania.

Department of Physiology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, Cluj-Napoca, Romania.

出版信息

Cell Mol Life Sci. 2017 Oct;74(19):3467-3479. doi: 10.1007/s00018-017-2532-y. Epub 2017 May 23.

DOI:10.1007/s00018-017-2532-y
PMID:28536787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11107489/
Abstract

Multidrug-resistant bacterial infections that have evolved via natural selection have increased alarmingly at a global level. Thus, there is a strong need for the development of novel antibiotics for the treatment of these infections. Functionalized carbon nanotubes through their unique properties hold great promise in the fight against multidrug-resistant bacterial infections. This new family of nanovectors for therapeutic delivery proved to be innovative and efficient for the transport and cellular translocation of therapeutic molecules. The current review examines the latest progress in the antibacterial activity of carbon nanotubes and their composites.

摘要

通过自然选择进化而来的多重耐药细菌感染在全球范围内惊人地增加。因此,迫切需要开发新型抗生素来治疗这些感染。功能化碳纳米管凭借其独特性能在对抗多重耐药细菌感染方面极具潜力。这种用于治疗递送的新型纳米载体家族被证明在治疗分子的运输和细胞转运方面具有创新性和高效性。本综述考察了碳纳米管及其复合材料抗菌活性的最新进展。

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本文引用的文献

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ACS Appl Mater Interfaces. 2016 Nov 30;8(47):32108-32119. doi: 10.1021/acsami.6b07770. Epub 2016 Nov 18.
2
Facile Synthesis of Au-Coated Magnetic Nanoparticles and Their Application in Bacteria Detection via a SERS Method.Au-Coated 磁性纳米粒子的简便合成及其在基于 SERS 方法的细菌检测中的应用。
ACS Appl Mater Interfaces. 2016 Aug 10;8(31):19958-67. doi: 10.1021/acsami.6b07528. Epub 2016 Jul 26.
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Selective Laser Ablation of Methicillin-Resistant Staphylococcus Aureus with IgG Functionalized Multi-Walled Carbon Nanotubes.用IgG功能化多壁碳纳米管对耐甲氧西林金黄色葡萄球菌进行选择性激光消融
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Beyond Antibiotics: New Therapeutic Approaches for Bacterial Infections.超越抗生素:细菌感染的新治疗方法
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Fibrin-targeting peptide CREKA-conjugated multi-walled carbon nanotubes for self-amplified photothermal therapy of tumor.纤维蛋白靶向肽 CREKA 修饰的多壁碳纳米管用于肿瘤的自增强光热治疗。
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Specific targeting and noninvasive imaging of breast cancer stem cells using single-walled carbon nanotubes as novel multimodality nanoprobes.利用单壁碳纳米管作为新型多模态纳米探针,对乳腺癌干细胞进行特异性靶向和非侵入性成像。
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Magnetic-optical nanohybrids for targeted detection, separation, and photothermal ablation of drug-resistant pathogens.用于靶向检测、分离和光热消融耐药病原体的磁光纳米杂化物。
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