碳纳米管作为抗菌剂。
Carbon nanotubes as anti-bacterial agents.
作者信息
Mocan Teodora, Matea Cristian T, Pop Teodora, Mosteanu Ofelia, Buzoianu Anca Dana, Suciu Soimita, Puia Cosmin, Zdrehus Claudiu, Iancu Cornel, Mocan Lucian
机构信息
Department of Nanomedicine, "Octavian Fodor" Gastroenterology Institute, 19-21 Croitorilor Street, Cluj-Napoca, Romania.
Department of Physiology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, Cluj-Napoca, Romania.
出版信息
Cell Mol Life Sci. 2017 Oct;74(19):3467-3479. doi: 10.1007/s00018-017-2532-y. Epub 2017 May 23.
Abstract
Multidrug-resistant bacterial infections that have evolved via natural selection have increased alarmingly at a global level. Thus, there is a strong need for the development of novel antibiotics for the treatment of these infections. Functionalized carbon nanotubes through their unique properties hold great promise in the fight against multidrug-resistant bacterial infections. This new family of nanovectors for therapeutic delivery proved to be innovative and efficient for the transport and cellular translocation of therapeutic molecules. The current review examines the latest progress in the antibacterial activity of carbon nanotubes and their composites.
摘要
通过自然选择进化而来的多重耐药细菌感染在全球范围内惊人地增加。因此，迫切需要开发新型抗生素来治疗这些感染。功能化碳纳米管凭借其独特性能在对抗多重耐药细菌感染方面极具潜力。这种用于治疗递送的新型纳米载体家族被证明在治疗分子的运输和细胞转运方面具有创新性和高效性。本综述考察了碳纳米管及其复合材料抗菌活性的最新进展。
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