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化脓性汗腺炎:2005年至2015年期间,在巴西东南部圣保罗州包鲁市一家皮肤科转诊中心确诊病例的流行病学研究。

Hidradenitis suppurativa: epidemiological study of cases diagnosed at a dermatological reference center in the city of Bauru, in the Brazilian southeast State of São Paulo, between 2005 and 2015.

作者信息

Andrade Tatiana Cristina Pedro Cordeiro de, Vieira Bruna Cortinóvis, Oliveira Agnes Mayumi Nakano, Martins Tábata Yamasaki, Santiago Tatiane Meira, Martelli Antônio Carlos Ceribelli

机构信息

Department of Dermatology, Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.

出版信息

An Bras Dermatol. 2017 Mar-Apr;92(2):196-199. doi: 10.1590/abd1806-4841.20175588.

DOI:10.1590/abd1806-4841.20175588
PMID:28538878
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5429104/
Abstract

BACKGROUND

: Hidradenitis is a chronic inflammatory disease of the hair follicles. A treatment is necessary due to chronicity and psychological changes that patient present.

OBJECTIVE

: To investigate epidemiological aspects and elaborate a risk group profile, promote early diagnosis and contribute to the knowledge about the disease.

METHODS

: This cross-sectional descriptive study with retrospective analysis of medical records of 194 patients diagnosed with hidrosadenitis in a dermatological reference center in the city of Bauru (SP) between 2005 and 2015.

RESULTS

: Females accounted for 74% of cases. The age at diagnosis ranged from 10 to 67 years and the majority was within the 3rd and 4th decade of life. It occurred Association with diabetes mellitus in 33%, obesity in 55% and smoking in 61% was observed. Mean time between the onset of the disease and diagnosis was nine years. Hurley stage II was the most common at diagnosis. The therapeutic option mostly used in Hurley I and II was systemic antibiotics and in Hurley III was surgery.

STUDY LIMITATIONS

: the main limitation of this study is its retrospective design, which does not allow the true clinical confirmation of the disease by investigators.

CONCLUSION

: we outlined the following profile: women, caucasian, between 3rd and 4th decade of life, associated with obesity, smoking, late diagnosis and multiple potential therapeutic modalities. We highlight the importance of studies like this in order to identify risk groups and encourage early diagnosis.

摘要

背景

化脓性汗腺炎是一种毛囊的慢性炎症性疾病。鉴于其慢性病程以及患者出现的心理变化,治疗是必要的。

目的

调查流行病学特征并制定风险人群概况,促进早期诊断并增进对该疾病的了解。

方法

本横断面描述性研究对2005年至2015年间在包鲁市(圣保罗州)一家皮肤科参考中心诊断为化脓性汗腺炎的194例患者的病历进行回顾性分析。

结果

女性占病例的74%。诊断时的年龄范围为10至67岁,大多数患者处于第三和第四个十年年龄段。观察到33%的患者与糖尿病有关,55%的患者肥胖,61%的患者吸烟。疾病发作与诊断之间的平均时间为9年。Hurley II期是诊断时最常见的阶段。Hurley I期和II期最常用的治疗选择是全身用抗生素,Hurley III期是手术。

研究局限性

本研究的主要局限性在于其回顾性设计,这使得研究人员无法对疾病进行真正的临床确诊。

结论

我们勾勒出了以下概况:女性、白种人、处于第三和第四个十年年龄段、与肥胖、吸烟、诊断延迟以及多种潜在治疗方式相关。我们强调此类研究对于识别风险人群和鼓励早期诊断的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/010523e1fa98/abd-92-02-0196-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/e747923ab7be/abd-92-02-0196-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/0dcc73a8d6ec/abd-92-02-0196-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/95cbf1d74aa0/abd-92-02-0196-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/4e93878f24fa/abd-92-02-0196-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/eed5607228b0/abd-92-02-0196-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/010523e1fa98/abd-92-02-0196-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/e747923ab7be/abd-92-02-0196-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/0dcc73a8d6ec/abd-92-02-0196-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/95cbf1d74aa0/abd-92-02-0196-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/4e93878f24fa/abd-92-02-0196-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/eed5607228b0/abd-92-02-0196-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3a7/5429104/010523e1fa98/abd-92-02-0196-g06.jpg

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本文引用的文献

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Dermatol Clin. 2016 Jan;34(1):7-16. doi: 10.1016/j.det.2015.08.002.
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Pathophysiology of hidradenitis suppurativa: An update.化脓性汗腺炎的病理生理学:更新。
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Recurrence of hidradenitis suppurativa after surgical management: A systematic review and meta-analysis.化脓性汗腺炎手术后复发的系统评价和荟萃分析。
揭示化脓性汗腺炎误诊和漏诊的负担:一种机器学习方法。
Front Med Technol. 2024 Mar 25;6:1200400. doi: 10.3389/fmedt.2024.1200400. eCollection 2024.
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Navigating the Multidimensional Impact of Living with Hidradenitis Suppurativa: An In-Depth Netnographic Study on Social Media Platforms.探究化脓性汗腺炎患者生活的多维影响:一项关于社交媒体平台的深度网络民族志研究
Dermatol Ther (Heidelb). 2023 Nov;13(11):2797-2815. doi: 10.1007/s13555-023-01032-9. Epub 2023 Oct 4.
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Prevalence of low vitamin D levels in patients with Hidradenitis suppurativa in Jordan: A comparative cross-sectional study.约旦化脓性汗腺炎患者维生素 D 水平低下的患病率:一项比较性横断面研究。
PLoS One. 2022 Mar 18;17(3):e0265672. doi: 10.1371/journal.pone.0265672. eCollection 2022.
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Therapies for hidradenitis suppurativa: a systematic review with a focus on Brazil.化脓性汗腺炎的治疗:一项以巴西为重点的系统评价
Drugs Context. 2022 Jan 19;11. doi: 10.7573/dic.2021-9-6. eCollection 2022.
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Clinical manifestations and quality of life in hidradenitis suppurativa patients: survey of participants from an internet support group.化脓性汗腺炎患者的临床表现及生活质量:来自一个互联网支持小组参与者的调查
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