Nik Narieman, Fong Amelia, Derdzakyan Marianna, Adamopoulou Chrysavgi, Sise Adam, Khanifar Aziz, Sanders Reginald
Department of Ophthalmology and Visual Sciences, Georgetown University/MedStar Washington Hospital Center, Washington, DC, USA.
Private Practice, Silver Spring, Maryland, USA.
J Ophthalmic Vis Res. 2017 Apr-Jun;12(2):183-186. doi: 10.4103/jovr.jovr_165_16.
To assess choroidal perfusion before and after orbital decompression surgery in patients with Graves' ophthalmopathy.
In this interventional case series, surgical decompression for optic nerve compromise was performed on four eyes of three patients with Graves' disease. Complete ophthalmic examination including visual acuity, color vision, and intraocular pressure assessment were done pre- and postoperatively. High-speed indocyanine green angiography was performed prior to surgery and was repeated one year after surgery.
In all three patients, choroidal perfusion defects were noted pre-operatively in the eyes with the compressive optic neuropathy. At 1 year after orbital decompression surgery, the defects improved or completely resolved. Improved visual acuity and color perception, as well as decreased intraocular pressure, were also noted postoperatively.
Patients with Graves' orbitopathy may have abnormal choroidal perfusion even in the absence of optic neuropathy. Orbital decompression may improve choroidal circulation in these patients.
评估格雷夫斯眼病患者眼眶减压手术前后的脉络膜灌注情况。
在这个介入性病例系列中，对3例格雷夫斯病患者的4只眼睛进行了视神经减压手术。术前和术后均进行了包括视力、色觉和眼压评估在内的全面眼科检查。术前进行了高速吲哚菁绿血管造影，并在术后1年重复进行。
所有3例患者中，术前患有压迫性视神经病变的眼睛均发现脉络膜灌注缺损。眼眶减压手术后1年，缺损得到改善或完全消失。术后还观察到视力和色觉改善，眼压降低。
即使没有视神经病变，格雷夫斯眼眶病患者也可能存在脉络膜灌注异常。眼眶减压可能改善这些患者的脉络膜循环。
