Faria-Correia Fernando, Lopes Bernardo, Monteiro Tiago, Franqueira Nuno, Ambrósio Renato
Ophthalmology Department, Hospital de Braga, Braga, Portugal.
Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal.
Int Ophthalmol. 2018 Jun;38(3):1103-1110. doi: 10.1007/s10792-017-0566-7. Epub 2017 May 26.
To assess the correlations between preoperative Scheimpflug-based lens densitometry and effective phacoemulsification time (EPT) in age-related nuclear cataracts.
Retrospective consecutive study.
The setting was the Ophthalmology Department, Hospital de Braga, Portugal. The study population included 50 eyes (42 patients) with age-related nuclear cataracts submitted to uneventful phacoemulsification surgery. Different analysis methods of Scheimpflug-based lens densitometry were performed: Pentacam Nucleus Staging (PNS) score with an ordinal scale from 0 to 5 and three-dimensional (3D), linear and region of interest (ROI) methods, which are displayed on an absolute scale (from 0 to 100%). EPT was calculated for the cataract surgery, which was performed by the same surgeon. Correlations between lens densitometry variables and EPT were determined using Pearson or Spearman correlation coefficients according to data normality.
There were significant correlations between EPT and average density and maximum density variables derived from the 3D (r = 0.596, p < 0.001; r = 0.632, p < 0.001, respectively) and ROI (r = 0.527, p < 0.001; r = 0.575, p < 0.001, respectively) methods. The average density was the only parameter derived from the linear analysis that showed a significant correlation with EPT (r = 0.293, p = 0.039). The PNS score did not show a significant correlation with EPT (rho = 0.124, p = 0.390).
The densitometric parameters based on the 3D method showed the highest correlations with EPT. The referred lens densitometric analysis approach may be used in preoperative assessment in order to predict EPT more efficiently in age-related nuclear cataracts.
评估基于Scheimpflug的晶状体密度测量法与年龄相关性核性白内障有效超声乳化时间(EPT)之间的相关性。
回顾性连续研究。
研究地点为葡萄牙布拉加医院眼科。研究人群包括50只眼(42例患者),均为接受了顺利超声乳化手术的年龄相关性核性白内障患者。采用了基于Scheimpflug的晶状体密度测量法的不同分析方法:Pentacam晶状体核分级(PNS)评分,其序数范围为0至5;以及三维(3D)、线性和感兴趣区域(ROI)方法,这些方法以绝对标度(从0至100%)显示。计算了由同一位外科医生进行的白内障手术的EPT。根据数据正态性,使用Pearson或Spearman相关系数确定晶状体密度测量变量与EPT之间的相关性。
EPT与通过3D方法得出的平均密度和最大密度变量之间存在显著相关性(分别为r = 0.596,p < 0.001;r = 0.632,p < 0.001),与ROI方法也存在显著相关性(分别为r = 0.527,p < 0.001;r = 0.575,p < 0.001)。平均密度是线性分析得出的唯一与EPT存在显著相关性的参数(r = 0.293,p = 0.039)。PNS评分与EPT未显示出显著相关性(rho = 0.124,p = 0.390)。
基于3D方法的密度测量参数与EPT的相关性最高。所提及的晶状体密度测量分析方法可用于术前评估,以便更有效地预测年龄相关性核性白内障的EPT。