Li Yuxueyun, Feng Yi, Li Fan, Xue Zidong, Hu Jing, Xing Hui, Ruan Yuhua, Shao Yiming
1 State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention , Beijing, China .
2 School of Public Health, Guangxi Medical University , Nanning, China .
AIDS Res Hum Retroviruses. 2017 Oct;33(10):1056-1060. doi: 10.1089/aid.2017.0066. Epub 2017 May 30.
We report a novel HIV-1 circulating recombinant form (CRF79_0107) from three epidemiologically unlinked patients through sexual contact in Shanxi province of China. This is the first second-generation circulating recombinant form identified in China. The breakpoint analysis of recombinants showed that CRF79_0107 was composed of CRF01_AE and CRF07_BC, with three CRF07_BC segments inserted into the CRF01_AE backbone. The emergence of CRF79_0107 increases the complexity of the HIV epidemic in China.
我们报告了一种新型的HIV-1循环重组型（CRF79_0107），它来自中国山西省三名在流行病学上无关联的通过性接触感染的患者。这是在中国鉴定出的首个第二代循环重组型。重组体的断点分析表明，CRF79_0107由CRF01_AE和CRF07_BC组成，有三个CRF07_BC片段插入到CRF01_AE主干中。CRF79_0107的出现增加了中国HIV流行的复杂性。
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