Haykowsky Mark J, Scott Jessica M, Hudson Kathryn, Denduluri Neelima
From the College of Nursing and Health Innovation, The University of Texas at Arlington, Arlington, TX; Memorial Sloan Kettering Cancer Center, New York, NY; US Oncology Network, Texas Oncology, Austin, TX; US Oncology Network, Virginia Cancer Specialists, Arlington, VA.
Am Soc Clin Oncol Educ Book. 2017;37:57-64. doi: 10.1200/EDBK_175349.
As patients are living longer after a cancer diagnosis, survivorship is becoming increasingly important in cancer care. The sequelae of multimodality therapies include weight gain and decreased cardiorespiratory fitness, which increase cardiovascular risk. Evidence suggests that physical activity reduces the risk of breast cancer recurrence and death. Avoidance of weight gain after therapy also improves outcomes after a diagnosis of breast cancer. Prospective randomized trials must be performed to determine the benefits of specific physical activity and dietary habits for survivors of breast cancer. This review outlines the important physiologic changes that occur with antineoplastic therapy and the important role of exercise and diet.
随着癌症诊断后患者的寿命延长，癌症幸存者护理在癌症治疗中变得越来越重要。多模式疗法的后遗症包括体重增加和心肺功能下降，这会增加心血管风险。有证据表明，体育活动可降低乳腺癌复发和死亡风险。治疗后避免体重增加也可改善乳腺癌诊断后的预后。必须进行前瞻性随机试验，以确定特定体育活动和饮食习惯对乳腺癌幸存者的益处。本综述概述了抗肿瘤治疗后发生的重要生理变化以及运动和饮食的重要作用。
