Ryu Ki Jin, Park Hyuntae, Park Jin Seol, Lee Yeon Woo, Kim Soo Young, Kim Hayun, Jeong Youngmi, Kim Yong Jin, Yi Kyong Wook, Shin Jung Ho, Hur Jun Young, Kim Tak
Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea.
Korea University College of Medicine, Seoul, Korea.
J Menopausal Med. 2020 Dec;26(3):147-153. doi: 10.6118/jmm.20030.
Vasomotor symptoms (VMS), such as hot flashes and night sweating, are classic menopausal symptoms experienced by a majority of perimenopausal and postmenopausal women. VMS have received a great deal of attention due to their relationship with cardiometabolic risk. Further, accumulating evidence indicates that VMS are associated with an increased risk of several chronic diseases, including metabolic syndrome, type 2 diabetes mellitus, nonalcoholic fatty liver diseases, and osteoporosis in perimenopausal and postmenopausal women. These findings suggest VMS as biomarkers of impaired cardiometabolic conditions rather than just temporary symptoms in menopausal women, warranting further studies to confirm the casual relationship of VMS with these diseases and the exact underlying mechanism in this context.
血管舒缩症状(VMS),如潮热和盗汗,是大多数围绝经期和绝经后女性经历的典型更年期症状。由于VMS与心脏代谢风险相关,因此受到了广泛关注。此外,越来越多的证据表明,VMS与几种慢性疾病的风险增加有关,包括围绝经期和绝经后女性的代谢综合征、2型糖尿病、非酒精性脂肪性肝病和骨质疏松症。这些发现表明,VMS是心脏代谢状况受损的生物标志物,而不仅仅是更年期女性的暂时症状,这需要进一步研究来证实VMS与这些疾病之间的因果关系以及在此背景下的确切潜在机制。