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正常衰老过程中的认知衰退及其预防:关于非药物生活方式策略的综述

Cognitive decline in normal aging and its prevention: a review on non-pharmacological lifestyle strategies.

作者信息

Klimova Blanka, Valis Martin, Kuca Kamil

机构信息

Department of Applied Linguistics, Faculty of Informatics and Management, University of Hradec Kralove.

Department of Neurology.

出版信息

Clin Interv Aging. 2017 May 25;12:903-910. doi: 10.2147/CIA.S132963. eCollection 2017.

Abstract

The purpose of this study is to examine the effects of the selected non-pharmacological lifestyle activities on the delay of cognitive decline in normal aging. This was done by conducting a literature review in the four acknowledged databases Web of Science, Scopus, MEDLINE, and Springer, and consequently by evaluating the findings of the relevant studies. The findings show that physical activities, such as walking and aerobic exercises, music therapy, adherence to Mediterranean diet, or solving crosswords, seem to be very promising lifestyle intervention tools. The results indicate that non-pharmacological lifestyle intervention activities should be intense and possibly done simultaneously in order to be effective in the prevention of cognitive decline. In addition, more longitudinal randomized controlled trials are needed in order to discover the most effective types and the duration of these intervention activities in the prevention of cognitive decline, typical of aging population groups.

摘要

本研究的目的是探讨所选非药物生活方式活动对延缓正常衰老过程中认知衰退的影响。通过在四个公认的数据库(科学网、Scopus、医学期刊数据库和施普林格)中进行文献综述,并进而评估相关研究的结果来实现这一目的。研究结果表明,诸如散步和有氧运动、音乐疗法、坚持地中海饮食或解谜等体育活动似乎是非常有前景的生活方式干预工具。结果表明,非药物生活方式干预活动应该强度较大,并且可能需要同时进行,以便在预防认知衰退方面有效。此外,需要更多的纵向随机对照试验,以发现这些干预活动在预防老年人群典型认知衰退方面最有效的类型和持续时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc09/5448694/13304f0c0521/cia-12-903Fig1.jpg

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