Dunbar J A, Ogston S A, Ritchie A, Devgun M S, Hagart J, Martin B T
Br Med J (Clin Res Ed). 1985 Mar 16;290(6471):827-30. doi: 10.1136/bmj.290.6471.827.
Serum gamma glutamyltranspeptidase activity was measured in 440 drivers at the time of arrest for driving under the influence of alcohol. The results were compared with information gathered by the arresting police officer. One third of drivers over the age of 30 had abnormal gamma glutamyltranspeptidase activities at the time of arrest. Among drivers who required a driving license for their work, and older drivers, a disproportionately high number had raised gamma glutamyltranspeptidase activities indicating problem drinking. In drivers over the age of 30 a strong association was found between gamma glutamyltranspeptidase activities and road traffic accidents but not alcohol concentrations or previous convictions. These findings argue against the Department of Transport's criteria for high risk offenders and indicate a clear need for new measures against problem drinkers among drinking and driving offenders.
对440名因酒后驾车被捕的司机进行了血清γ-谷氨酰转肽酶活性检测。将结果与逮捕他们的警官收集的信息进行了比较。三分之一年龄超过30岁的司机在被捕时γ-谷氨酰转肽酶活性异常。在需要驾驶执照工作的司机以及年长司机中,γ-谷氨酰转肽酶活性升高表明存在饮酒问题的人数比例过高。在30岁以上的司机中,发现γ-谷氨酰转肽酶活性与道路交通事故之间存在密切关联,但与酒精浓度或先前定罪无关。这些发现与运输部对高危罪犯的标准相悖,表明显然需要采取新措施来应对酒驾罪犯中的酗酒者。