Bellucci Roberto, Curatolo Maria C
J Refract Surg. 2017 Jun 1;33(6):389-394. doi: 10.3928/1081597X-20170329-01.
To describe a new extended depth of focus intraocular lens (IOL) design offering multifocality by the variation of spherical aberration in the central optical zone.
The new IOL (Mini WELL; SIFI, Catania, Italy) is an aspheric IOL with positive spherical aberration in the central 2-mm zone and negative spherical aberration in the pericentral 1-mm annulus, the amount of which was determined by specific optic calculation. The new IOL design was tested at the optical bench to investigate depth of focus and sensitivity to tilt, decentration, and angle Kappa. Visual acuity simulations were obtained from distance (4 m) to near (0.5 m).
Modulation transfer function (MTF) for a 3-mm pupil was 0.35 to 0.40 for distance vision and 0.25 to 0.30 for intermediate and near vision. MTF for a 4.5-mm pupil was 0.40 to 0.55 and 0.10 to 0.20, respectively. These values were not influenced by tilt up to ±2.5°, by decentration up to ±0.5 mm, or by angle Kappa up to 9°. Visual acuity simulations indicated good visual acuity up to 2.00 D of pseudoaccommodation.
The new IOL with double spherical aberration in the central 3-mm zone offered good MTF over a wide dioptric interval, suggesting good visual acuity between 4 m and 50 cm. This extended depth of focus IOL with no diffractive rings is expected to produce lower unwanted optical phenomena than current multifocal IOLs. [J Refract Surg. 2017;33(6):389-394.].
描述一种新型的扩展焦深人工晶状体（IOL）设计，该设计通过中央光学区球差的变化实现多焦点功能。
新型IOL（Mini WELL；意大利卡塔尼亚市的SIFI公司）是一种非球面IOL，其在中央2毫米区域具有正球差，在中央周围1毫米环形区域具有负球差，其数值通过特定的光学计算确定。在光具座上对新型IOL设计进行测试，以研究焦深以及对倾斜、偏心和kappa角的敏感度。从远距（4米）到近距（0.5米）获得视力模拟结果。
对于3毫米瞳孔，远距视力的调制传递函数（MTF）为0.35至0.40，中距和近距视力的MTF为0.25至0.30。对于4.5毫米瞳孔，MTF分别为0.40至0.55和0.10至0.20。这些值不受高达±2.5°的倾斜、高达±0.5毫米的偏心或高达9°的kappa角的影响。视力模拟表明，在高达2.00 D的伪调节范围内视力良好。
在中央3毫米区域具有双球差的新型IOL在较宽的屈光度区间内提供了良好的MTF，表明在4米至50厘米之间视力良好。这种没有衍射环且扩展焦深的IOL预计会比当前的多焦点IOL产生更少的不良光学现象。[《屈光手术杂志》。2017年；33（6）：389 - 394。]
