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哈扎拉地区哮喘患者代谢综合征的发病率

Frequency Of Metabolic Syndrome In Asthmatic Patients Of Hazara Division.

作者信息

Ahmed Nasir, Kazim Syed Moosa, Gillani Syed Yasir

机构信息

Department of Medicine, Ayub Medical College, Abbottabad, Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2016 Oct-Dec;28(4):762-765.

PMID:28586602
Abstract

BACKGROUND

Bronchial asthma is a common disease and most asthmatics are obese. Both asthma and obesity are showing parallel trends in their increasing prevalence. Obesity is also the main component of metabolic syndrome and several studies have shown metabolic syndrome to be associated with bronchial asthma. The present study was, therefore, designed to determine the frequency of metabolic syndrome among patients with chronic asthma in our setup.

METHODS

This cross-sectional study was conducted in Department of Medicine, Ayub Teaching Hospital, Abbottabad from May to November, 2014. One hundred and fifty-four asthmatic patients were enrolled in this study. Samples for blood glucose, triglycerides and HDL Cholesterol were taken after an overnight fast. Sitting blood pressure was measured with mercury sphygmomanometer after 10 minutes of rest. Waist circumference was measured at the level of the midpoint between the high point of the iliac crest and the last rib.

RESULTS

Out of 154 patients, 80 were males and 74 were females. Metabolic syndrome was diagnosed in 46 (29.87%) patients. When metabolic syndrome was stratified according to age, sex and duration of asthma, the results were found to be insignificant (p-0.89, 0.30 and 0.85).

CONCLUSIONS

This study showed that metabolic syndrome was present in almost one third of study population.

摘要

背景

支气管哮喘是一种常见疾病,大多数哮喘患者肥胖。哮喘和肥胖的患病率都呈平行上升趋势。肥胖也是代谢综合征的主要组成部分,多项研究表明代谢综合征与支气管哮喘有关。因此,本研究旨在确定我们机构中慢性哮喘患者代谢综合征的发生率。

方法

这项横断面研究于2014年5月至11月在阿伯塔巴德阿尤布教学医院内科进行。本研究纳入了154例哮喘患者。空腹过夜后采集血糖、甘油三酯和高密度脂蛋白胆固醇样本。休息10分钟后用汞柱血压计测量坐位血压。在髂嵴高点和最后一根肋骨之间的中点水平测量腰围。

结果

154例患者中,男性80例,女性74例。46例(29.87%)患者被诊断为代谢综合征。当根据年龄、性别和哮喘病程对代谢综合征进行分层时,结果无统计学意义(p分别为0.89、0.30和0.85)。

结论

本研究表明,近三分之一的研究人群存在代谢综合征。

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引用本文的文献

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Association of Asthma With Patients Diagnosed With Metabolic Syndrome: A Cohort Study in a Tertiary Care Hospital.哮喘与诊断为代谢综合征患者的关联:一项三级护理医院的队列研究。
Cureus. 2023 Oct 24;15(10):e47558. doi: 10.7759/cureus.47558. eCollection 2023 Oct.
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Asthma and metabolic syndrome: a comprehensive systematic review and meta-analysis of observational studies.哮喘与代谢综合征:观察性研究的全面系统综述与荟萃分析
J Cardiovasc Thorac Res. 2020;12(2):120-128. doi: 10.34172/jcvtr.2020.20. Epub 2020 May 31.