Macpherson Helen, Teo Wei-P, Schneider Luke A, Smith Ashleigh E
Institute for Physical Activity and Nutrition, Deakin UniversityBurwood, VIC, Australia.
Robinson Research Institute, University of AdelaideAdelaide, SA, Australia.
Front Aging Neurosci. 2017 May 23;9:147. doi: 10.3389/fnagi.2017.00147. eCollection 2017.
It is well established that engaging in lifelong Physical activity (PA) can help delay the onset of many chronic lifestyle related and non-communicable diseases such as cardiovascular disease, type two diabetes, cancer and chronic respiratory diseases. Additionally, growing evidence also documents the importance of PA for brain health, with numerous studies indicating regular engagement in physical activities may be protective against cognitive decline and dementia in late life. Indeed, the link between PA and brain health may be different at each stage of life from childhood, mid-life and late life. Building on this emerging body of multidisciplinary research, this review aims to summarize the current body of evidence linking regular PA and brain health across the lifespan. Specifically, we will focus on the relationship between PA and brain health at three distinct stages of life: childhood and adolescence, mid-life, late life in cognitively healthy adults and later life in adults living with age-related neurodegenerative disorders such as Parkinson's disease (PD) and Alzheimer's disease (AD).
众所周知，坚持终身体育活动（PA）有助于延缓许多与慢性生活方式相关的非传染性疾病的发病，如心血管疾病、2型糖尿病、癌症和慢性呼吸道疾病。此外，越来越多的证据也证明了体育活动对大脑健康的重要性，大量研究表明，经常进行体育活动可能有助于预防晚年的认知能力下降和痴呆症。事实上，体育活动与大脑健康之间的联系在人生的每个阶段可能都有所不同，从童年、中年到晚年。基于这一新兴的多学科研究成果，本综述旨在总结目前关于终身定期体育活动与大脑健康之间联系的证据。具体而言，我们将关注体育活动与大脑健康在三个不同生命阶段的关系：儿童和青少年时期、中年、认知健康成年人的晚年以及患有帕金森病（PD）和阿尔茨海默病（AD）等与年龄相关的神经退行性疾病的成年人的晚年。
