Coates D
J Hosp Infect. 1985 Mar;6(1):31-40. doi: 10.1016/s0195-6701(85)80015-3.
A comparison of commercial sodium hypochlorite (NaOCl) and sodium dichloroisocyanurate (NaDCC) products was made. Solutions of NaOCl and NaDCC containing the same levels of available chlorine (av.Cl) exhibited very similar bactericidal activities, despite significant differences in pH. A level of 12.5 ppm av. Cl achieved a greater than 5 log 10 reduction of Staphylococcus aureus in 2 min. A level of 5 ppm av.Cl achieved a greater than 5 log 10 reduction of Pseudomonas aeruginosa in 2 min whilst approximately 100 ppm av.Cl achieved the same reduction in the presence of 1% horse serum, and approximately 200 ppm av.Cl in the presence of 2% horse serum, indicating inactivation levels of around 95 and 97.5% respectively. Tablets of NaDCC were stable but solutions were unstable and decomposed much faster than NaOCl solutions of the same strength. Batch-to-batch variability of different NaOCl and NaDCC products was investigated; whilst NaDCC products always contained the minimum level of av.Cl specified, concentrated NaOCl products sometimes did not due to inherent instability.
对市售次氯酸钠(NaOCl)和二氯异氰尿酸钠(NaDCC)产品进行了比较。尽管pH值存在显著差异,但含有相同有效氯(av.Cl)水平的NaOCl和NaDCC溶液表现出非常相似的杀菌活性。12.5 ppm的av.Cl水平在2分钟内可使金黄色葡萄球菌减少超过5个对数10。5 ppm的av.Cl水平在2分钟内可使铜绿假单胞菌减少超过5个对数10,而在1%马血清存在下约100 ppm的av.Cl可达到相同的减少效果,在2%马血清存在下约200 ppm的av.Cl可达到相同的减少效果,分别表明灭活水平约为95%和97.5%。NaDCC片剂稳定,但溶液不稳定,且比相同浓度的NaOCl溶液分解得快得多。研究了不同NaOCl和NaDCC产品的批次间差异;虽然NaDCC产品始终含有规定的最低av.Cl水平,但由于固有的不稳定性,浓缩NaOCl产品有时并非如此。