Evaluation of antimicrobial efficacy of sodium dichloroisocyanurate as an intracanal medicament against and .

BACKGROUND

Various formulations of medicaments have been used to eradicate and in secondary endodontic infection. Sodium dichloroisocyanurate (NaDCC) has proven potency to act against . However, research against both and as an intracanal medicament at different time intervals is yet to be evaluated.

AIM

The aim of this study was to compare and evaluate the antimicrobial efficacy of NaDCC against and .

MATERIALS AND METHODS

Ninety-six mandibular single-rooted premolars were randomly divided into two groups for inoculation of and . They were then divided into four groups: Group 1 was treated with ketoconazole, Group 2 with NaDCC, Group 3 with calcium hydroxide (CH), and Group 4 with 2% chlorhexidine. These medicaments were placed inside the root canal using lentulo spirals, sealed, and incubated under aerobic conditions. At the end of 3 and 7 days, the antimicrobial efficacy was assessed by calculating the colony forming unit/mL (CFU/ml) against and using a digital colony counter. Analysis of variance and paired -test were used for statistical analysis.

RESULTS

NaDCC exhibited superior results against E. faecalis and C. albicans after 3 and 7 days compared to chlorhexidine and CH.

CONCLUSION

NaDCC can be considered a potential alternative to calcium hydroxide and chlorhexidine as an intracanal medicament for effective root canal disinfection and in secondary endodontic infection.