Cardiology Division, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, China.
Department of Medicine (Cardiovascular Division), University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sci Rep. 2017 Jun 9;7(1):3196. doi: 10.1038/s41598-017-03377-6.
The size and function of the left atrium (LA) and right atrium (RA) are related closely with the prognosis of cardiovascular diseases. However, their normal reference values, as measured by cardiac magnetic resonance (CMR), are not well established in Chinese populations. Healthy Chinese subjects (n = 135, 66 males, age 23-83 years) without cardiovascular risk factors were recruited. We imaged the LA and RA of all subjects using short axis and long axis slices by steady-state free precession (SSFP) sequences using a 3.0T scanner. The size and functional parameters were measured. Age and gender differences in LA were further explored. The normal reference values of atrial dimensions, volumes, and empty fractions (EFs) were provided by short axis (SAX) and area-length methods. Volumes and EFs derived by the area-length method showed correlated well with those derived by the by SAX method, but significantly underestimated the volumes (all P < 0.001) and overestimated the LA EFs (all P < 0.001). Atrial dimensions and volumes were generally larger in males. Conduit EFs and total EFs showed gender differences. Most atrial parameters correlated with age. In general, our results showed that gender and age have considerable impact on LA and RA size and function.
左心房（LA）和右心房（RA）的大小和功能与心血管疾病的预后密切相关。然而，在中国人中，心脏磁共振（CMR）测量的正常参考值尚未得到很好的确立。本研究纳入了 135 名无心血管危险因素的健康中国受试者（66 名男性，年龄 23-83 岁）。使用 3.0T 扫描仪的稳态自由进动（SSFP）序列对所有受试者进行短轴和长轴切片成像，测量 LA 和 RA 的大小和功能参数。进一步探讨了 LA 的年龄和性别差异。通过短轴（SAX）和面积-长度法提供了心房尺寸、容量和排空分数（EF）的正常参考值。面积-长度法得出的容量和 EF 与 SAX 法得出的结果相关性良好，但明显低估了容量（均 P < 0.001），高估了 LA EF（均 P < 0.001）。男性的心房尺寸和容量通常较大。传导 EF 和总 EF 存在性别差异。大多数心房参数与年龄相关。一般来说，我们的研究结果表明，性别和年龄对 LA 和 RA 的大小和功能有很大影响。
