Shahid Mohammad, Kundra Rik
St Michael's Hospital, 30 Bond Street, Toronto, M5B1W8, Canada.
EFORT Open Rev. 2017 Mar 13;2(1):28-34. doi: 10.1302/2058-5241.2.160004. eCollection 2017 Jan.
Platelet-rich plasma (PRP) is an autologous blood product with platelet concentrations above baseline values. The process involves the extraction of blood from the patient which is then centrifuged to obtain a concentrated suspension of platelets by plasmapheresis. It then undergoes a two-stage centrifugation process to separate the solid and liquid components of the anticoagulated blood. PRP owes its therapeutic use to the growth factors released by the platelets which are claimed to possess multiple regenerative properties.In the knee, PRP has been used in patients with articular cartilage pathology, ligamentous and meniscal injuries.There is a growing body of evidence to support its use in selected indications and this review looks at the most recent evidence. We also look at the current UK National Institute of Health & Clinical Excellence (NICE) guidelines with respect to osteoarthritis and the use of PRP in the knee. Cite this article: 2017;2:28-34. DOI: 10.1302/2058-5241.2.160004.
富血小板血浆（PRP）是一种血小板浓度高于基线值的自体血液制品。该过程包括从患者体内抽取血液，然后通过血浆置换术进行离心，以获得浓缩的血小板悬浮液。接着，它要经过两阶段离心过程，以分离抗凝血液的固体和液体成分。PRP的治疗用途归因于血小板释放的生长因子，据称这些生长因子具有多种再生特性。在膝关节方面，PRP已用于患有关节软骨病变、韧带和半月板损伤的患者。越来越多的证据支持其在特定适应症中的应用，本综述将探讨最新证据。我们还将审视英国国家卫生与临床优化研究所（NICE）目前关于骨关节炎以及膝关节PRP使用的指南。引用本文：2017；2：28 - 34。DOI：10.1302/2058 - 5241.2.160004。
