State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9517-9521. doi: 10.1002/anie.201703841. Epub 2017 Jul 6.
A catalytic intermolecular allylic C-H trifluoromethoxylation reaction of alkenes has been developed based on the use of a palladium catalyst, CsOCF as the trifluoromethoxide source, and benzoquinone as the oxidant. This reaction provides an efficient route for directly accessing allylic trifluoromethoxy derivatives with excellent regioselectivities from terminal alkenes via an allylic C-H bond activation process.
一种基于钯催化剂、CsOCF 作为三氟甲氧基源以及苯醌作为氧化剂的催化的烯丙基 C-H 三氟甲氧基化反应已经被开发出来。该反应提供了一种从末端烯烃通过烯丙基 C-H 键活化过程直接获得具有优异区域选择性的烯丙基三氟甲氧基衍生物的有效途径。
