Janzon L, Franzén J, Lindell S E, Trell E
Postgrad Med J. 1985 Jun;61(716):505-8. doi: 10.1136/pgmj.61.716.505.
Carboxyhaemoglobin (COHb%) and gamma-glutamyl-transferase (GGT) are today frequently used as objective indicators of tobacco and alcohol consumption. The relationships between COHb%, GGT and relative body weight, cholesterol, triglyceride and apolipoprotein AI (Apo-AI) were studied in middle-aged men attending a preventive medical programme in Malmö, Sweden. Although statistically significant the influence of COHb% on cholesterol and triglyceride was found to be clinically insignificant. GGT and body weight had, independent of each other, a significant influence on cholesterol and triglyceride. GGT was found to have a positive correlation to Apo-AI whereas body weight was found to have a negative correlation to Apo-AI. Four per cent of the cholesterol variability, 16% of the triglyceride variability and about 10% of the variability in Apo-AI could, in this study, be accounted for by COHb%, GGT and relative body weight.
如今，碳氧血红蛋白（COHb%）和γ-谷氨酰转移酶（GGT）常被用作烟草和酒精消费的客观指标。在瑞典马尔默参加预防医疗项目的中年男性中，研究了COHb%、GGT与相对体重、胆固醇、甘油三酯和载脂蛋白AI（Apo-AI）之间的关系。尽管COHb%对胆固醇和甘油三酯的影响在统计学上具有显著性，但在临床上却不显著。GGT和体重相互独立地对胆固醇和甘油三酯有显著影响。研究发现GGT与Apo-AI呈正相关，而体重与Apo-AI呈负相关。在本研究中，COHb%、GGT和相对体重可解释4%的胆固醇变异性、16%的甘油三酯变异性和约10%的Apo-AI变异性。
