Janzon L, Lindell S E, Trell E, Larme P
J Epidemiol Community Health. 1981 Dec;35(4):271-3. doi: 10.1136/jech.35.4.271.
In this cross-sectional population study we report on the distribution of carboxyhaemoglobin concentrations in the morning, before smoking, in an urban population of 1037 men born in 1931. The median concentration was the same in non-smokers as in ex-smokers: 0.5%. It increased with increasing daily tobacco consumption. But when carboxyhaemoglobin concentrations are measured in reasonably well-standardised circumstances there are large variations between individuals, even in those who smoke equal amounts of tobacco a day. This makes it difficult to predict the concentration in the individual smoker when only his daily tobacco consumption is known. Measurements of carboxyhaemoglobin concentration should be a valuable complement to smoking history to identify the smoker at high risk of cardiovascular disease, to provide an extra argument to make the patient give up the habit, and to reinforce the efforts of those who try to do so.
在这项横断面人群研究中，我们报告了1931年出生的1037名城市男性在早晨吸烟前的碳氧血红蛋白浓度分布情况。非吸烟者和已戒烟者的中位数浓度相同：0.5%。它随着每日烟草消费量的增加而升高。但是，当在相当标准化的情况下测量碳氧血红蛋白浓度时，个体之间存在很大差异，即使是那些每天吸烟量相同的人。因此，仅知道个体吸烟者的每日烟草消费量时，很难预测其体内的碳氧血红蛋白浓度。测量碳氧血红蛋白浓度应该是吸烟史的一个有价值的补充，用于识别心血管疾病高危吸烟者，为促使患者戒烟提供额外依据，并加强那些努力帮助患者戒烟者的工作。
