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克罗恩病:通过饮食维持缓解

Crohn's disease: maintenance of remission by diet.

作者信息

Jones V A, Dickinson R J, Workman E, Wilson A J, Freeman A H, Hunter J O

出版信息

Lancet. 1985 Jul 27;2(8448):177-80. doi: 10.1016/s0140-6736(85)91497-7.

Abstract

20 patients with Crohn's disease took part in a controlled trial in which remission was maintained by either an unrefined carbohydrate fibre rich diet or a diet which excluded specific foods to which a patient was intolerant. 7 out of the 10 patients on the exclusion diet remained in remission for 6 months compared with none out of the 10 on an unrefined carbohydrate fibre rich diet (p less than 0.05, Fisher's exact test). In an uncontrolled study an exclusion diet allowed 51 out of 77 patients to remain well on the diet alone for periods of up to 51 months, and with an average annual relapse rate of less than 10%.

摘要

20名克罗恩病患者参与了一项对照试验,试验中通过富含未精制碳水化合物纤维的饮食或排除患者不耐受的特定食物的饮食来维持缓解状态。采用排除饮食的10名患者中有7名在6个月内保持缓解,而采用富含未精制碳水化合物纤维饮食的10名患者中无人保持缓解(P<0.05,Fisher精确检验)。在一项非对照研究中,一种排除饮食使77名患者中的51名仅通过饮食就保持良好状态达51个月,且年复发率低于10%。

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