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未精制富含碳水化合物和纤维的饮食对克罗恩病的多中心对照治疗试验

Controlled multicentre therapeutic trial of an unrefined carbohydrate, fibre rich diet in Crohn's disease.

作者信息

Ritchie J K, Wadsworth J, Lennard-Jones J E, Rogers E

机构信息

St Mark's Hospital, London.

出版信息

Br Med J (Clin Res Ed). 1987 Aug 29;295(6597):517-20. doi: 10.1136/bmj.295.6597.517.

DOI:10.1136/bmj.295.6597.517
PMID:2822203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1247426/
Abstract

Between 1 September 1980 and 31 August 1983, 352 patients with inactive or mildly active Crohn's disease but not taking drug treatment apart from sulphasalazine were entered from 40 hospitals into a prospective trial to assess the effects of two different diets on disease activity over two years. One hundred and sixty two patients were randomly allocated to take a diet unrestricted in sugar and low in fibre and 190 to a diet with little or no sugar and high in unrefined carbohydrate. No clear difference in clinical course was detected among patients who accepted the two different types of dietary advice.

摘要

1980年9月1日至1983年8月31日期间，来自40家医院的352例非活动期或轻度活动期克罗恩病患者（除柳氮磺胺吡啶外未接受药物治疗）进入一项前瞻性试验，以评估两种不同饮食在两年内对疾病活动的影响。162例患者被随机分配采用糖无限制、纤维含量低的饮食，190例患者采用糖含量低或无糖、未精制碳水化合物含量高的饮食。接受两种不同饮食建议的患者在临床病程上未发现明显差异。

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本文引用的文献

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Increased sugar consumption in Crohn's disease.克罗恩病中糖分摄入量增加。
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Z Gastroenterol. 1981 Jan;19(1):1-12.
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Gut. 1984 Jun;25(6):665-72. doi: 10.1136/gut.25.6.665.
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Elemental diet as primary treatment of acute Crohn's disease: a controlled trial.要素饮食作为急性克罗恩病的主要治疗方法：一项对照试验。
Br Med J (Clin Res Ed). 1984 Jun 23;288(6434):1859-62. doi: 10.1136/bmj.288.6434.1859.
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The diet of individuals: a study of a randomly-chosen cross section of British adults in a Cambridgeshire village.
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A simple index of Crohn's-disease activity.克罗恩病活动度的简易指数。
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Low residue or normal diet in Crohn's disease: a prospective controlled study in Italian patients.克罗恩病患者的低残渣或正常饮食：一项针对意大利患者的前瞻性对照研究
Gut. 1985 Oct;26(10):989-93. doi: 10.1136/gut.26.10.989.