Heaton K W, Thornton J R, Emmett P M
Br Med J. 1979 Sep 29;2(6193):764-6. doi: 10.1136/bmj.2.6193.764.
Thirty-two patients with Crohn's disease were treated with a fibre-rich, unrefined-carbohydrate diet in addition to conventional management and followed for a mean of four years and four months. Their clinical course was compared retrospectively with that of 32 matched patients who had received no dietary instruction. Hospital admissions were significantly fewer and shorter in the diet-treated patients, who spent a total of 111 days in hospital compared with 533 days in the non-diet-treated control group. Whereas five of the controls required intestinal operation, only one diet-treated patient needed surgery. This is in strong contrast to general experience with this disease. Treatment with a fibre-rich, unrefined-carbohydrate diet appears to have a favourable effect on the course of Crohn's disease and does not lead to intestinal obstruction.
32例克罗恩病患者在接受常规治疗的基础上，采用富含纤维的未精制碳水化合物饮食进行治疗，并随访了平均四年零四个月。将他们的临床病程与32例匹配的未接受饮食指导的患者进行回顾性比较。接受饮食治疗的患者住院次数明显更少，住院时间也更短，他们总共住院111天，而未接受饮食治疗的对照组住院时间为533天。对照组中有5人需要进行肠道手术，而接受饮食治疗的患者中只有1人需要手术。这与该病的一般经验形成了强烈对比。采用富含纤维的未精制碳水化合物饮食进行治疗似乎对克罗恩病的病程有积极影响，且不会导致肠梗阻。
