Yamakawa Hideaki, Suido Yoshihiro, Sadoyama Shinko, Yamanaka Yumie, Ikeda Satoshi, Kitamura Hideya, Baba Tomohisa, Okudela Koji, Takemura Tamiko, Ogura Takashi
Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Department of Respiratory Medicine, Tokyo Jikei University Hospital, Japan.
Intern Med. 2017;56(12):1553-1556. doi: 10.2169/internalmedicine.56.8110. Epub 2017 Jun 15.
As an idiopathic interstitial pneumonia, desquamative interstitial pneumonia (DIP) is an uncommon form of interstitial lung disease and is considered to be a smoking- or dust inhalation-related interstitial pneumonia in the majority of cases. However, the details regarding immunoglobulin G4 (IgG4)-related lung disease remain unclear and controversial. We herein report the first case of DIP complicated with IgG4-related lung disease. Even if a patient has a smoking history, we emphasize the importance of exploring the association between DIP and IgG4-related lung disease to clarify the pathogenesis of these two disorders.
作为一种特发性间质性肺炎，脱屑性间质性肺炎（DIP）是间质性肺疾病的一种罕见形式，在大多数情况下被认为是与吸烟或吸入粉尘相关的间质性肺炎。然而，关于免疫球蛋白G4（IgG4）相关肺疾病的细节仍不清楚且存在争议。我们在此报告首例合并IgG4相关肺疾病的DIP病例。即使患者有吸烟史，我们仍强调探索DIP与IgG4相关肺疾病之间关联以阐明这两种疾病发病机制的重要性。
