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肥胖变量在伊朗人群高血压检测中的作用

Role of Obesity Variables in Detecting Hypertension in an Iranian Population.

作者信息

Khashayar Patricia, Aghaei Meybodi Hamidreza, Rezaei Hemami Mohsen, Larijani Bagher

机构信息

Osteoporosis Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Center for Microsystems Technology, Imec and Ghent University, Zwijnaarde, Ghent, Belgium.

出版信息

High Blood Press Cardiovasc Prev. 2017 Sep;24(3):305-312. doi: 10.1007/s40292-017-0219-y. Epub 2017 Jun 22.

Abstract

INTRODUCTION

As the high incidence of hypertension has been in conjunction with dramatic increase in the prevalence of obesity, many studies have suggested obesity as its underlying cause in diverse race and ethnic groups.

AIM

The present study was designed to quantify the relationship between obesity variables and hypertension in Iranian population. A ROC curve analysis was also used to determine an optimal BMI cutoff for obesity with the aim of representing elevated incidence of hypertension in this population.

METHODS

The study population comprised of apparently healthy men and women who participated in the Iranian Multi-centric Osteoporosis Studies (IMOS), a multi-centric cross-sectional study carried out in urban areas of five great cities (Tehran, Tabriz, Mashhad, Shiraz and Bushehr). The anthropometric (weight, height, waist and hip circumferences) and blood pressure measures were reported in some 5724 subjects. The influence of these factors on systolic and diastolic blood pressure was assessed based on a list-wise method.

RESULTS

There was a significant difference in the studied subjects anthropometric (weight classes (BMI), WC and HC, and WHR) and blood pressure variables; age, gender and weight, however, were the only factors significantly influencing SBP and DBP. Furthermore, BMI showed a significant impact on the overall risk of developing hypertension.

CONCLUSION

General obesity rather than abdominal obesity is directly linked with higher blood pressure levels in Iranian population.

摘要

引言

由于高血压的高发病率与肥胖患病率的急剧增加同时出现,许多研究表明肥胖是不同种族和族裔群体患高血压的潜在原因。

目的

本研究旨在量化伊朗人群中肥胖变量与高血压之间的关系。还使用ROC曲线分析来确定肥胖的最佳BMI临界值,以反映该人群中高血压的高发病率。

方法

研究人群包括参与伊朗多中心骨质疏松症研究(IMOS)的明显健康的男性和女性,这是一项在五个大城市(德黑兰、大不里士、马什哈德、设拉子和布什尔)的城市地区进行的多中心横断面研究。约5724名受试者报告了人体测量数据(体重、身高、腰围和臀围)和血压测量值。基于列表法评估这些因素对收缩压和舒张压的影响。

结果

研究对象的人体测量数据(体重类别(BMI)、腰围和臀围以及腰臀比)和血压变量存在显著差异;然而,年龄、性别和体重是仅有的显著影响收缩压和舒张压的因素。此外,BMI对患高血压的总体风险有显著影响。

结论

在伊朗人群中,全身性肥胖而非腹部肥胖与较高的血压水平直接相关。

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