Zeng Fan-Gang
IEEE Trans Biomed Eng. 2017 Aug;64(8):1662-1664. doi: 10.1109/TBME.2017.2718939. Epub 2017 Jun 22.
Here I identify two gaps in cochlear implants that have been limiting their performance and acceptance. First, cochlear implant performance has remained largely unchanged, despite the number of publications tripling per decade in the last 30 years. Little has been done so far to address a fundamental limitation in the electrode-to-neuron interface, with the electrode size being a thousand times larger than the neuron diameter while the number of electrodes being a thousand times less. Both the small number and the large size of electrodes produce broad spatial activation and poor frequency resolution that limit current cochlear implant performance. Second, a similarly rapid growth in cochlear implant volume has not produced an expected decrease in unit price in the same period. The high cost contributes to low market penetration rate, which is about 20% in developed countries and less than 1% in developing countries. I will discuss changes needed in both research strategy and business practice to close the gap between prosthetic and normal hearing as well as that between haves and have-nots.
在此,我指出了人工耳蜗存在的两个缺陷,这些缺陷一直在限制其性能和接受度。首先,尽管在过去30年里,相关出版物的数量每十年就增加两倍,但人工耳蜗的性能在很大程度上仍未改变。到目前为止,在解决电极与神经元接口的一个基本限制方面几乎没有取得什么进展,电极尺寸比神经元直径大一千倍,而电极数量却比神经元数量少一千倍。电极数量少且尺寸大,导致空间激活范围广且频率分辨率差,这限制了当前人工耳蜗的性能。其次,人工耳蜗产量同样快速增长,却并未带来同期单价的预期下降。高昂的成本导致市场渗透率较低,在发达国家约为20%,在发展中国家则不到1%。我将讨论研究策略和商业实践中需要做出的改变,以弥合假体听力与正常听力之间以及贫富之间的差距。