Liu Jiang, Bao Tian-Yi, Yang Xi-Ya, Zhu Pei-Pei, Wu Lian-He, Sha Jing-Quan, Zhang Lei, Dong Long-Zhang, Cao Xue-Li, Lan Ya-Qian
Key Laboratory of Inorganic Chemistry in Universities of Shandong, Department of Chemistry and Chemical Engineering, Jining University, Qufu, Shandong 273155, P. R. China.
Chem Commun (Camb). 2017 Jul 6;53(55):7804-7807. doi: 10.1039/c7cc03673f.
Two extremely rare β-cyclodextrin (β-CD) supported metal-organic frameworks (MOFs), CD-MOF-1 and CD-MOF-2, were induced to crystallize for the first time through a template-induced approach. The targeted CD-MOFs were employed to perform controlled drug delivery and cytotoxicity assays that confirmed their favourable biological potential of being used as drug carriers.
通过模板诱导法首次诱导出两种极其罕见的β-环糊精（β-CD）负载金属有机框架（MOF），即CD-MOF-1和CD-MOF-2。所靶向的CD-MOF被用于进行可控药物递送和细胞毒性试验，证实了它们作为药物载体具有良好的生物学潜力。
