Carne C A, Tedder R S, Smith A, Sutherland S, Elkington S G, Daly H M, Preston F E, Craske J
Lancet. 1985 Nov 30;2(8466):1206-8. doi: 10.1016/s0140-6736(85)90740-8.
Acute encephalopathy was associated with the appearance of antibodies to human T-lymphotropic virus (HTLV-III) in two patients. A third patient showed seroconversion for anti-HTLV-III, but the temporal association was not established so precisely. The illness was characterised by a prodromal period of up to 2 weeks, characterised by pyrexia, general malaise, and changes of mood. The encephalopathy culminated in epileptiform seizures in two of the patients. Electroencephalographic changes were compatible with viral encephalitis, and cerebrospinal-fluid pleocytosis was minimal. Neurological signs and symptoms resolved quickly in all patients, and no residual central-nervous-system sequelae were apparent.
两名患者的急性脑病与人类嗜T淋巴细胞病毒（HTLV-III）抗体的出现有关。第三名患者出现了抗HTLV-III的血清学转换，但时间关联没有如此精确地确定。该病的特点是前驱期长达2周，表现为发热、全身不适和情绪变化。两名患者的脑病最终发展为癫痫样发作。脑电图变化与病毒性脑炎相符，脑脊液细胞数轻度增多。所有患者的神经体征和症状迅速缓解，且未出现明显的中枢神经系统后遗症。
