人类健康中的暴露组范式：埃默里暴露组暑期课程的经验教训。
The Exposome Paradigm in Human Health: Lessons from the Emory Exposome Summer Course.
作者信息
Niedzwiecki Megan M, Miller Gary W
机构信息
Department of Environmental Health, Rollins School of Public Health, Emory University , Atlanta, Georgia, USA.
出版信息
Environ Health Perspect. 2017 Jun 29;125(6):064502. doi: 10.1289/EHP1712.
Abstract
The environment plays a major role in human health, yet tools to study the health impacts of complex environmental exposures are lacking. In 2005, Christopher Wild introduced the concept of the exposome, which encompasses environmental exposures and concomitant biological responses throughout the life course. Exposome-based approaches have the potential to enable novel insights into numerous research questions in environmental health sciences. To promote and develop the concept of the exposome, the Health and Exposome Research Center: Understanding Lifetime Exposures (HERCULES) Exposome Research Center at Emory University held the first Emory Exposome Summer Course from 13-17 June 2016. https://doi.org/10.1289/EHP1712.
摘要
环境在人类健康中起着主要作用，但目前仍缺乏研究复杂环境暴露对健康影响的工具。2005年，克里斯托弗·怀尔德提出了暴露组的概念，它涵盖了整个生命过程中的环境暴露及相应的生物学反应。基于暴露组的方法有可能为环境卫生科学中的众多研究问题带来新的见解。为了推广和发展暴露组的概念，埃默里大学的健康与暴露组研究中心：了解终生暴露（HERCULES）暴露组研究中心于2016年6月13日至17日举办了首届埃默里暴露组暑期课程。https://doi.org/10.1289/EHP1712
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