Maheshwari Rajesh, Tracy Mark, Hinder Murray, Wright Audrey
Department of Neonatology, Westmead Hospital, Sydney, New South Wales, Australia.
J Paediatr Child Health. 2017 Aug;53(8):761-765. doi: 10.1111/jpc.13609. Epub 2017 Jul 4.
The aim of this study was to compare mask leak with three different peak inspiratory pressure (PIP) settings during T-piece resuscitator (TPR; Neopuff) mask ventilation on a neonatal manikin model.
Participants were neonatal unit staff members. They were instructed to provide mask ventilation with a TPR with three PIP settings (20, 30, 40 cm H O) chosen in a random order. Each episode was for 2 min with 2-min rest period. Flow rate and positive end-expiratory pressure (PEEP) were kept constant. Airway pressure, inspiratory and expiratory tidal volumes, mask leak, respiratory rate and inspiratory time were recorded. Repeated measures analysis of variance was used for statistical analysis.
A total of 12 749 inflations delivered by 40 participants were analysed. There were no statistically significant differences (P > 0.05) in the mask leak with the three PIP settings. No statistically significant differences were seen in respiratory rate and inspiratory time with the three PIP settings. There was a significant rise in PEEP as the PIP increased. Failure to achieve the desired PIP was observed especially at the higher settings.
In a neonatal manikin model, the mask leak does not vary as a function of the PIP when the flow rate is constant. With a fixed rate and inspiratory time, there seems to be a rise in PEEP with increasing PIP.
本研究旨在比较在新生儿人体模型上使用T形管复苏器(TPR;Neopuff)面罩通气时,三种不同的吸气峰压(PIP)设置下的面罩漏气情况。
参与者为新生儿病房工作人员。他们被要求使用TPR以随机顺序选择的三种PIP设置(20、30、40 cm H₂O)进行面罩通气。每次通气持续2分钟,中间休息2分钟。流速和呼气末正压(PEEP)保持恒定。记录气道压力、吸气和呼气潮气量、面罩漏气、呼吸频率和吸气时间。采用重复测量方差分析进行统计分析。
共分析了40名参与者进行的12749次通气。三种PIP设置下的面罩漏气情况无统计学显著差异(P > 0.05)。三种PIP设置下的呼吸频率和吸气时间也无统计学显著差异。随着PIP的增加,PEEP有显著升高。尤其在较高设置下,观察到未能达到所需的PIP。
在新生儿人体模型中,当流速恒定时,面罩漏气不会随PIP的变化而变化。在固定的频率和吸气时间下,随着PIP的增加,PEEP似乎会升高。