Miazek Krystian, Kratky Lukas, Sulc Radek, Jirout Tomas, Aguedo Mario, Richel Aurore, Goffin Dorothee
TERRA, AgricultureIsLife, University of Liege-Gembloux Agro-Bio Tech, Passage des Déportés 2, Gembloux B-5030, Belgium.
Faculty of Mechanical Engineering, Department of Process Engineering, Czech Technical University in Prague, Technická 4, 166 07 Prague 6, Czech Republic.
Int J Mol Sci. 2017 Jul 4;18(7):1429. doi: 10.3390/ijms18071429.
In this review, the effect of organic solvents on microalgae cultures from molecular to industrial scale is presented. Traditional organic solvents and solvents of new generation-ionic liquids (ILs), are considered. Alterations in microalgal cell metabolism and synthesis of target products (pigments, proteins, lipids), as a result of exposure to organic solvents, are summarized. Applications of organic solvents as a carbon source for microalgal growth and production of target molecules are discussed. Possible implementation of various industrial effluents containing organic solvents into microalgal cultivation media, is evaluated. The effect of organic solvents on extraction of target compounds from microalgae is also considered. Techniques for lipid and carotenoid extraction from viable microalgal biomass (milking methods) and dead microalgal biomass (classical methods) are depicted. Moreover, the economic survey of lipid and carotenoid extraction from microalgae biomass, by means of different techniques and solvents, is conducted.
在本综述中，介绍了有机溶剂对从分子规模到工业规模的微藻培养的影响。文中考虑了传统有机溶剂和新一代溶剂——离子液体（ILs）。总结了微藻细胞代谢以及因接触有机溶剂而导致的目标产物（色素、蛋白质、脂质）合成的变化。讨论了有机溶剂作为微藻生长的碳源以及目标分子生产的应用。评估了将各种含有有机溶剂的工业废水用于微藻培养基的可能性。还考虑了有机溶剂对从微藻中提取目标化合物的影响。描述了从活微藻生物质（挤奶法）和死微藻生物质（经典方法）中提取脂质和类胡萝卜素的技术。此外，还对通过不同技术和溶剂从微藻生物质中提取脂质和类胡萝卜素进行了经济调查。
