Alencar Catarina Ribeiro Barros de, Oliveira Gabriela Cristina de, Magalhães Ana Carolina, Buzalaf Marília Afonso Rabelo, Machado Maria Aparecida de Andrade Moreira, Honório Heitor Marques, Rios Daniela
Universidade Estadual da Paraíba, Departamento de Odontologia, Araruna, PB, Brasil.
Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Odontopediatria, Ortodontia e Saúde Coletiva, Bauru, SP, Brasil.
J Appl Oral Sci. 2017 May-Jun;25(3):258-264. doi: 10.1590/1678-7757-2016-0304.
This in situ study investigated the ability of a CPP-ACP chewing gum in preventing erosive enamel loss. Material and Methods: During three experimental crossover phases (one phase per group) of seven days each, eight volunteers wore palatal devices with human enamel blocks. The groups were: GI - Sugar free chewing gum with CPP-ACP; GII - Conventional sugar free chewing gum; and GIII - No chewing gum (control). Erosive challenge was extraorally performed by immersion of the enamel blocks in cola drink (5 min, 4x/day). After each challenge, in groups CPP and No CPP, volunteers chewed one unit of the corresponding chewing gum for 30 minutes. Quantitative analysis of enamel loss was performed by profilometry (µm). Data were analyzed by Repeated-Measures ANOVA and Tukey's test (p<0.05).
The use of chewing gum (CPP and No CPP) resulted in lower erosive enamel loss compared with the control group (p<0.05). CPP-ACP chewing gum (CPP) did not improve the protection against erosive enamel loss compared with conventional chewing gum (No CPP) (p>0.05).
The CPP-ACP chewing gum was not able to enhance the anti-erosive effect of conventional chewing gum against enamel loss.
本原位研究调查了含酪蛋白磷酸肽-无定形磷酸钙（CPP-ACP）的口香糖预防牙釉质侵蚀性流失的能力。材料与方法：在三个各为期七天的实验交叉阶段（每组一个阶段）中，八名志愿者佩戴带有人类牙釉质块的腭部装置。分组如下：GI组——含CPP-ACP的无糖口香糖；GII组——传统无糖口香糖；GIII组——不使用口香糖（对照组）。通过将牙釉质块浸入可乐饮料中（5分钟，每天4次）在体外进行侵蚀性刺激。每次刺激后，在使用CPP组和未使用CPP组中，志愿者咀嚼一单位相应的口香糖30分钟。通过轮廓测定法（微米）对牙釉质流失进行定量分析。数据采用重复测量方差分析和Tukey检验进行分析（p<0.05）。
与对照组相比，使用口香糖（CPP组和未使用CPP组）导致的牙釉质侵蚀性流失更低（p<0.05）。与传统口香糖（未使用CPP组）相比，含CPP-ACP的口香糖（CPP组）在预防牙釉质侵蚀性流失方面并未表现出更好的保护效果（p>0.05）。
含CPP-ACP的口香糖无法增强传统口香糖对牙釉质流失的抗侵蚀作用。
