Behrouzi Parastou, Heshmat Haleh, Hoorizad Ganjkar Maryam, Tabatabaei Seyedeh Farnaz, Kharazifard Mohammad Javad
Dentist, Tehran, Iran.
Dental Material Research Center of Tehran University of Medical Sciences, Dept. of Restorative and Cosmetic Dentistry, Islamic Azad University, Tehran, Iran.
J Dent (Shiraz). 2020 Mar;21(1):12-17. doi: 10.30476/DENTJODS.2019.77864.
The progression of incipient carious lesions may be simply prevented by non-invasive remineralization of lesions, eliminating the need for invasive and high-cost restorative procedures.
This study aimed to assess the effect of two commonly used remineralizing agents and resin infiltration on surface micro hardness of incipient enamel lesions at different time points.
In this study, 45 intact human maxillary central incisors were selected. After disinfection, enamel samples measuring 5x5x2.5 mm were cut out of the labial surface of the teeth. The surface of samples was polished and they were mounted in auto-polymerizing acrylic resin. According to Amaechi's method, samples were immersed in acidified hydroxyethylcellulose system (pH= 4.5) for 96 hours to induce white spot lesions (WSLs). The baseline value of surface micro hardness of samples was measured using a Vickers hardness tester, then the samples were randomly divided into three groups (n=15) based on different remineralization methods: MI-Paste Plus, Remin Pro and ICON-Infiltrant according to the manufacturer's instructions. All samples were stored in anti-dry mouth treatment agent during the experiment and their surface hardness was measured at 15 days (T1) and 20 weeks (T2).
The hardness of samples in MI-Paste Plus and Remin Pro groups significantly increased at both T1 and T2 (< 0.001) but this increase was not significant in ICON group (> 0.05).
MI-Paste Plus and Remin Pro can efficiently increase the hardness of incipient enamel lesions.
通过对早期龋损进行非侵入性再矿化，可以简单地预防早期龋损的进展，从而无需进行侵入性且成本高昂的修复程序。
本研究旨在评估两种常用的再矿化剂和树脂渗透对早期釉质龋损在不同时间点表面显微硬度的影响。
在本研究中，选取了45颗完整的人类上颌中切牙。消毒后，从牙齿唇面切出尺寸为5×5×2.5毫米的釉质样本。对样本表面进行抛光，并将其嵌入自凝丙烯酸树脂中。根据阿玛奇的方法，将样本浸泡在酸化羟乙基纤维素系统（pH = 4.5）中96小时以诱导白斑病变（WSLs）。使用维氏硬度测试仪测量样本表面显微硬度的基线值，然后根据不同的再矿化方法将样本随机分为三组（n = 15）：按照制造商的说明分别为MI-Paste Plus、Remin Pro和ICON-Infiltrant。在实验过程中，所有样本均保存在抗口干治疗剂中，并在第15天（T1）和第20周（T2）测量其表面硬度。
MI-Paste Plus组和Remin Pro组样本在T1和T2时硬度均显著增加（< 0.001），但ICON组的这种增加不显著（> 0.05）。
MI-Paste Plus和Remin Pro可有效提高早期釉质龋损的硬度。
