Díaz-Gómez Jorge L, Castorena-Torres Fabiola, Preciado-Ortiz Ricardo E, García-Lara Silverio
Agri-Foods Unit, Tecnologico de MonterreyMonterrey, Mexico.
Tecnologico de Monterrey, Escuela de MedicinaMonterrey, Mexico.
Front Chem. 2017 Jun 21;5:44. doi: 10.3389/fchem.2017.00044. eCollection 2017.
Cancer is one of the main chronic degenerative diseases worldwide. In recent years, consumption of whole-grain cereals and their derivative food products has been associated with a reduced risk of various types of cancer. The main biomolecules in cereals include proteins, peptides, and amino acids, all of which are present in different quantities within the grain. Some of these peptides possess nutraceutical properties and exert biological effects that promote health and prevent cancer. In this review, we report the current status and advances in knowledge regarding the bioactive properties of maize peptides, such as antioxidant, antihypertensive, hepatoprotective, and anti-tumor activities. We also highlight the potential biological mechanisms through which maize bioactive peptides exert anti-cancer activity. Finally, we analyze and emphasize the potential applications of maize peptides.
癌症是全球主要的慢性退行性疾病之一。近年来，食用全谷物及其衍生食品与降低各类癌症风险相关。谷物中的主要生物分子包括蛋白质、肽和氨基酸，它们在谷物中的含量各不相同。其中一些肽具有营养保健特性，并发挥促进健康和预防癌症的生物学作用。在本综述中，我们报告了关于玉米肽生物活性特性（如抗氧化、抗高血压、保肝和抗肿瘤活性）的现状和知识进展。我们还强调了玉米生物活性肽发挥抗癌活性的潜在生物学机制。最后，我们分析并强调了玉米肽的潜在应用。
