Javed F, Al-Kheraif A A, Kellesarian S V, Vohra F, Romanos G E
Department of General Dentistry, Eastman Institute for Oral Health, University of Rochester, NY, USA.
Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
J Biol Regul Homeost Agents. 2017 Apr-Jun;31(2):343-346.
The objective of this study was to assess the oral Candida carriage and species prevalence in denture stomatitis (DS) patients with and without diabetes mellitus (DM). To address the focused question “In patients receiving dentures, how does having diabetes compared to no diabetes influences the carriage and species prevalence of oral Candida?” Indexed databases were explored without time or language restrictions up to and including February 2017. Nine studies were included. In these studies, the number of diabetics ranged between 14 patients and 405 individuals with mean ages ranging between 33 years and 66.4 years. In five studies, the percentage of hyperglycemic patients in the diabetic group ranged from 14.3% to 100%. In one study, all diabetic patients were normoglycemic. Seven studies reported Candida-associated DS to be significantly higher among diabetics than non-diabetics. Candida albicans was the most prevalent species isolated among diabetics and non-diabetics with DS. Denture-wearers with DM are more susceptible to Candida-associated DS as compared to non-diabetics.
本研究的目的是评估患和未患糖尿病（DM）的义齿性口炎（DS）患者的口腔念珠菌携带情况及菌种流行率。为回答核心问题“在佩戴义齿的患者中，患糖尿病与未患糖尿病相比，如何影响口腔念珠菌的携带情况及菌种流行率？”，我们对截至2017年2月（含该月）的索引数据库进行了不受时间和语言限制的检索。共纳入9项研究。在这些研究中，糖尿病患者数量在14例至405例之间，平均年龄在33岁至66.4岁之间。在5项研究中，糖尿病组血糖升高患者的比例在14.3%至100%之间。在1项研究中，所有糖尿病患者血糖均正常。7项研究报告称，糖尿病患者中念珠菌相关性DS显著高于非糖尿病患者。白色念珠菌是在患和未患DS的糖尿病患者及非糖尿病患者中分离出的最常见菌种。与非糖尿病患者相比，佩戴义齿的糖尿病患者更易患念珠菌相关性DS。
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