含银填料对软性义齿衬里材料抗菌性能和力学性能的影响。

Effect of Silver-Emitting Filler on Antimicrobial and Mechanical Properties of Soft Denture Lining Material.

作者信息

Jabłońska-Stencel Ewa, Pakieła Wojciech, Mertas Anna, Bobela Elżbieta, Kasperski Jacek, Chladek Grzegorz

机构信息

Center of Dentistry and Implantology, ul. Karpińskiego 3, 41-500 Chorzów, Poland.

Faculty of Mechanical Engineering, Institute of Engineering Materials and Biomaterials, Silesian University of Technology, ul. Konarskiego 18a, 44-100 Gliwice, Poland.

出版信息

Materials (Basel). 2018 Feb 22;11(2):318. doi: 10.3390/ma11020318.

Colonization of silicone-based soft lining materials by pathogenic yeast-type fungi is a common problem associated with the use of dentures. In this study, silver sodium hydrogen zirconium phosphate (SSHZP) was introduced into polydimethylsiloxane-based material as an antimicrobial filler at concentrations of 0.25, 0.5, 1, 2, 4, 6, 8, 10, 12, and 14% (/). The in vitro antimicrobial efficacy was investigated. was used as a characteristic representative of pathogenic oral microflora. and were used as the typical Gram-positive and Gram-negative bacterial strains, respectively. The effect of filler addition on the Shore A hardness, tensile strength, tensile bond strength, sorption, and solubility was investigated. An increase in the filler concentration resulted in an increase in hardness, sorption, and solubility, and for the highest concentration, a decrease in bond strength. The favorable combination of antimicrobial efficacy with other properties was achieved at filler concentrations ranging from 2% to 10%. These composites exhibited mechanical properties similar to the material without the antimicrobial filler and enhanced in vitro antimicrobial efficiency.

致病性酵母型真菌在硅基软衬材料上的定植是与假牙使用相关的常见问题。在本研究中，将磷酸氢锆钠银（SSHZP）作为抗菌填料以0.25%、0.5%、1%、2%、4%、6%、8%、10%、12%和14%（/）的浓度引入聚二甲基硅氧烷基材料中。研究了其体外抗菌效果。变形链球菌被用作致病性口腔微生物群的特征代表。金黄色葡萄球菌和大肠杆菌分别被用作典型的革兰氏阳性和革兰氏阴性细菌菌株。研究了添加填料对邵氏A硬度、拉伸强度、拉伸粘结强度、吸附和溶解性的影响。填料浓度的增加导致硬度、吸附和溶解性增加，而对于最高浓度，粘结强度降低。在2%至10%的填料浓度范围内实现了抗菌效果与其他性能的良好组合。这些复合材料表现出与不含抗菌填料的材料相似的机械性能，并提高了体外抗菌效率。