天际线生态系统：定量质谱蛋白质组学信息学。
The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics.
机构信息
Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington.
出版信息
Mass Spectrom Rev. 2020 May;39(3):229-244. doi: 10.1002/mas.21540. Epub 2017 Jul 9.
Abstract
Skyline is a freely available, open-source Windows client application for accelerating targeted proteomics experimentation, with an emphasis on the proteomics and mass spectrometry community as users and as contributors. This review covers the informatics encompassed by the Skyline ecosystem, from computationally assisted targeted mass spectrometry method development, to raw acquisition file data processing, and quantitative analysis and results sharing.
摘要
Skyline 是一个免费的、开源的 Windows 客户端应用程序，用于加速靶向蛋白质组学实验，重点是将蛋白质组学和质谱社区作为用户和贡献者。这篇综述涵盖了 Skyline 生态系统所包含的信息学，从计算辅助靶向质谱方法开发，到原始采集文件数据处理，以及定量分析和结果共享。
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