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腰椎管内痛风石性痛风酷似硬膜外脊髓肿瘤

Tophaceous Gout in the Lumbar Spinal Canal Mimicking Epidural Spinal Tumor.

作者信息

Kim Taeshin, Kim Bum-Joon, Kim Se-Hoon, Lee Seung-Hwan

机构信息

Department of Neurosurgery, Korea University Ansan Hospital, Ansan, Korea.

出版信息

Korean J Spine. 2017 Jun;14(2):50-52. doi: 10.14245/kjs.2017.14.2.50. Epub 2017 Jun 30.

Abstract

Gout is an inflammatory arthritis characterized by deposition of monosodium urate crystals in joints. Though gout frequently involves the big toe or other extremities, it rarely occurs in the spinal canal. A 35-year-old man presented with left L5 radiculopathy. He had leg pain for 8 months and received several epidural steroid injections. Magnetic resonance imaging revealed a 1.7×1.1-cm ovoid contrast-enhancing mass, causing pressure erosion of the left L5 pedicle. Microscopic laminotomy was performed at the left L5 lamina. White chalky materials, identified at the left lateral recess of the spinal canal, were removed in a piecemeal manner. The histopathologic diagnosis was tophaceous gout. Although the patient's radiating pain did not resolve postoperatively, it was dramatically relieved with uric acid-lowering medications. If a mass effect is suspected, surgical removal of gouty tophi might aid in symptom release and definite diagnosis. Medical treatment after rheumatology consultation is crucial.

摘要

痛风是一种炎症性关节炎,其特征是关节内有尿酸钠晶体沉积。虽然痛风常累及大脚趾或其他肢体,但很少发生在椎管内。一名35岁男性出现左侧L5神经根病。他腿部疼痛8个月,接受了多次硬膜外类固醇注射。磁共振成像显示一个1.7×1.1厘米的椭圆形强化肿块,导致左侧L5椎弓根受压侵蚀。在左侧L5椎板进行了显微椎板切开术。在椎管左侧隐窝发现的白色粉笔样物质被逐块切除。组织病理学诊断为痛风石性痛风。虽然患者术后放射痛未缓解,但使用降尿酸药物后疼痛明显减轻。如果怀疑有占位效应,手术切除痛风石可能有助于缓解症状和明确诊断。风湿科会诊后的药物治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/715f/5518431/50543d9d308a/kjs-14-2-50f1.jpg

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