1 Department of Ultrasound, China-Japan Union Hospital of Jilin University, 126 Xiantai St, Changchun 130033, Jilin, China.
AJR Am J Roentgenol. 2017 Oct;209(4):775-780. doi: 10.2214/AJR.16.17626. Epub 2017 Jul 13.
The purposes of this study were to compare pancreatic shear-wave velocity (SWV) in subjects with and those without diabetic microvascular complications and to investigate the feasibility of pancreatic SWV in evaluating diabetic microangiopathy.
SWV measurements were prospectively performed in 115 patients with diabetes mellitus and 115 healthy persons by use of acoustic radiation force impulse imaging. Patients with diabetes were divided into subgroups with and without microangiopathy. Pancreatic SWV was compared in three groups. Factors associated with increased SWV were studied.
Pancreatic SWV increased significantly in the subgroups with diabetes mellitus compared with the control group (p < 0.01). Especially, the SWV in the pancreatic body was significantly higher when microangiopathy was present (p < 0.01). In patients with diabetes, microangiopathy (standardized β = 0.208, p = 0.022), age (standardized β = 0.265, p = 0.004), and total cholesterol level (standardized β = 0.223, p = 0.011) were positively and markedly correlated with high SWV in the pancreatic body.
The increased SWV in the pancreatic body was significantly related to the presence of microangiopathy. It is feasible to use SWV in the pancreatic body to evaluate diabetic microangiopathy.
本研究旨在比较伴有和不伴有糖尿病微血管并发症患者的胰腺剪切波速度（SWV），并探讨胰腺 SWV 评估糖尿病微血管病变的可行性。
采用声辐射力脉冲成像技术对 115 例糖尿病患者和 115 例健康者进行前瞻性 SWV 测量。将糖尿病患者分为伴有和不伴有微血管病变的亚组。比较三组的胰腺 SWV。研究与 SWV 升高相关的因素。
与对照组相比，糖尿病亚组的胰腺 SWV 显著升高（p<0.01）。特别是当存在微血管病变时，胰腺体部的 SWV 显著升高（p<0.01）。在糖尿病患者中，微血管病变（标准化β=0.208，p=0.022）、年龄（标准化β=0.265，p=0.004）和总胆固醇水平（标准化β=0.223，p=0.011）与胰腺体部的高 SWV 呈正相关且显著相关。
胰腺体部的 SWV 升高与微血管病变的存在密切相关。使用胰腺体部的 SWV 评估糖尿病微血管病变是可行的。
