OCD Institute for Children and Adolescents, McLean Hospital, Middleborough, MA, USA.
Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Depress Anxiety. 2017 Nov;34(11):1057-1064. doi: 10.1002/da.22672. Epub 2017 Jul 17.
Exposure and response prevention (ERP) is an effective treatment for individuals with obsessive-compulsive disorder (OCD), yet a substantial number of individuals with OCD do not fully respond to this intervention. Based on emerging experimental and clinical research on acceptance, this study sought to explore whether willingness to experience unpleasant thoughts, emotions, and bodily sensations during ERP was associated with improved treatment response.
Two hundred eighty-eight adults with OCD receiving residential ERP provided self-rated willingness and other exposure-related variables during each daily coached ERP session. Obsessive-compulsive and depressive symptom severity was assessed every week. Multilevel modeling was used to study the impact of willingness on treatment outcome during the first 6 weeks of residential care.
Data indicated that individuals with higher willingness during ERP reported faster symptom reduction during residential treatment, even when controlling for length of stay, psychopharmacological intervention, depression, adherence, and rituals performed during ERP. These results appear to have both statistical and clinical significance.
Willingness to fully experience unpleasant and unwanted thoughts, emotions, and bodily sensations during exposures appears to be a marker of successful exposure therapy in adults with OCD. Future research should examine how willingness may enhance extinction learning during ERP.
暴露和反应预防(ERP)是治疗强迫症(OCD)患者的有效方法,但仍有相当一部分 OCD 患者对这种干预措施没有完全反应。基于接受度的新兴实验和临床研究,本研究旨在探索在 ERP 过程中是否愿意体验不愉快的想法、情绪和身体感觉是否与改善治疗反应有关。
288 名接受住院 ERP 的 OCD 成年人在每次接受有指导的 ERP 治疗时,都会对自身的意愿和其他与暴露相关的变量进行自评。每周评估一次强迫症和抑郁症状的严重程度。使用多层次模型研究了在住院治疗的前 6 周内,意愿对治疗结果的影响。
数据表明,在 ERP 期间意愿更高的个体报告在住院治疗期间症状减轻更快,即使在控制住院时间、精神药理学干预、抑郁、依从性和 ERP 期间进行的仪式的情况下也是如此。这些结果似乎具有统计学和临床意义。
在暴露治疗过程中,愿意充分体验不愉快和不想要的想法、情绪和身体感觉,似乎是 OCD 成人成功暴露治疗的一个标志。未来的研究应探讨意愿如何增强 ERP 期间的消退学习。