McNeil Mark, Gerber Priscilla F, Thomson Jill, Williamson Susanna, Opriessnig Tanja
The Roslin Institute and The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, Scotland, United Kingdom.
The Roslin Institute and The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, Scotland, United Kingdom; Animal Science, School of Environmental and Rural Science, University of New England, Armidale, NSW, Australia.
Vet J. 2017 Jul;225:13-15. doi: 10.1016/j.tvjl.2017.04.012. Epub 2017 May 3.
Erysipelothrix spp. cause a range of clinical signs in pigs and at least 28 different Erysipelothrix spp. serotypes have been identified. In this study, 128 isolates of Erysipelothrix spp. from pigs in Great Britain from 1987 to 2015 were characterised by serotyping and multiplex real time PCR assays targeting the surface protective antigen (Spa) and the main genotypes (Erysipelothrix rhusiopathiae, Erysipelothrix tonsillarum and Erysipelothrix spp. strain 2). All 128 British isolates were characterised as E. rhusiopathiae and were classified as serotypes 1a (n=21), 1b (n=17), 2 (n=75), 5 (n=2), 9 (n=2), 10 (n=2), 11 (n=4) and 15 (n=1), while four isolates were untypeable. All isolates were positive for the spa A gene. Serotypes 1a, 1b and 2 constituted 88.3% of the isolates; current serotype 2 based vaccines should protect against these isolates.
猪丹毒丝菌属在猪身上会引发一系列临床症状，并且已鉴定出至少28种不同的猪丹毒丝菌属血清型。在本研究中，对1987年至2015年从英国猪身上分离出的128株猪丹毒丝菌属菌株进行了血清分型以及针对表面保护性抗原（Spa）和主要基因型（猪红斑丹毒丝菌、扁桃体丹毒丝菌和猪丹毒丝菌属菌株2）的多重实时PCR分析。所有128株英国分离株均被鉴定为猪红斑丹毒丝菌，并被分类为血清型1a（n = 21）、1b（n = 17）、2（n = 75）、5（n = 2）、9（n = 2）、10（n = 2）、11（n = 4）和15（n = 1），而有4株分离株无法分型。所有分离株的spa A基因均呈阳性。血清型1a、1b和2占分离株的88.3%；目前基于血清型2的疫苗应可预防这些分离株。
