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不同冠材料对根管治疗后磨牙龈沟液中白细胞介素-1β含量的影响:一项原创性研究

Effect of Different Crown Materials on the InterLeukin-One Beta Content of Gingival Crevicular Fluid in Endodontically Treated Molars: An Original Research.

作者信息

Saravanakumar Prathibha, Thallam Veeravalli Padmanabhan, Kumar V Anand, Mohamed Kasim, Mani Umamaheswari, Grover Manita, Thirumalai Thangarajan Saravanan

机构信息

Department of Prosthodontics, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India.

Prosthodontics, MN Dav,Tatul,Solan,Himachal Pradesh.

出版信息

Cureus. 2017 Jun 16;9(6):e1361. doi: 10.7759/cureus.1361.

DOI:10.7759/cureus.1361
PMID:28721329
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5510969/
Abstract

INTRODUCTION

Crown materials used in fixed prosthodontics come into close and prolonged contact with the gingiva.

OBJECTIVE

The purpose of this study was to evaluate the effect of different crown materials on the interleukin-one beta (IL-1β) content of the gingival crevicular fluid and to study which crown material causes the highest inflammation on the marginal gingiva on a biochemical basis.

MATERIALS AND METHODS

Twenty patients with single endodontically treated tooth were examined. Contralateral teeth were taken as controls. The crown materials in contact with the marginal gingiva were divided into three groups: Group 1- metal, Group2- ceramic, Group 3-zirconia. The collected data were analyzed with International Bibliography of the Social Sciences (IBSS). Statistical Package for the Social Sciences (SPSS) Statistics software 23.0 (IBM Corp, Armonk, New York). All assay procedures were carried out and the results of the collected samples were calculated using the ELISA-AID technique.

RESULTS

Multiple comparisons using one-way analysis of variance (ANOVA) between the materials on day zero, 45and 90 day was highly significant with p=0.0005. Pairwise comparison using Tukey's honest significant difference (HSD) posthoc test was also highly statistically significant with p= 0.0005 except for ceramic & zirconia which were significant at p=0.04 on the 90 day. Multiple comparison using repeated measure of ANOVA with Bonferroni correction between day zero, 45 and 90 day was found to be statistically significant only for zirconia (p=0.002).

CONCLUSION

This study was conducted to evaluate the effect of different crown materials on the amount of marginal gingival inflammation by measuring the IL-1β content in gingival crevicular fluid (GCF). At the end of the three-month analysis, it was seen that the zirconia crowns exhibited the least marginal gingival inflammation.

摘要

引言

固定修复中使用的牙冠材料与牙龈密切且长期接触。

目的

本研究旨在评估不同牙冠材料对龈沟液中白细胞介素 -1β(IL-1β)含量的影响,并从生化角度研究哪种牙冠材料对边缘牙龈引起的炎症最大。

材料与方法

检查了20名单侧牙髓治疗后的患者。对侧牙齿作为对照。与边缘牙龈接触的牙冠材料分为三组:第1组 - 金属,第2组 - 陶瓷,第3组 - 氧化锆。收集的数据使用《社会科学国际文献目录》(IBSS)进行分析。使用社会科学统计软件包(SPSS)统计软件23.0(IBM公司,纽约州阿蒙克)。所有检测程序均已进行,收集样本的结果使用ELISA - AID技术进行计算。

结果

在第0天、45天和90天,使用单因素方差分析(ANOVA)对材料进行多重比较,p = 0.0005,差异极显著。使用Tukey's诚实显著差异(HSD)事后检验进行两两比较,p = 0.0005时差异也极显著,除了陶瓷和氧化锆在第90天p = 0.04时差异显著。使用重复测量ANOVA并进行Bonferroni校正,在第0天、45天和90天之间进行多重比较,发现仅氧化锆具有统计学意义(p = 0.002)。

结论

本研究旨在通过测量龈沟液(GCF)中的IL-1β含量来评估不同牙冠材料对边缘牙龈炎症量的影响。在三个月的分析结束时,发现氧化锆牙冠表现出最少的边缘牙龈炎症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/0dad5c2281c4/cureus-0009-00000001361-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/5990e772bb79/cureus-0009-00000001361-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/360f3662a93b/cureus-0009-00000001361-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/aa9f43ea8f92/cureus-0009-00000001361-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/f6ee125e85e2/cureus-0009-00000001361-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/8e4d1c59c195/cureus-0009-00000001361-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/2090e14e2578/cureus-0009-00000001361-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/0dad5c2281c4/cureus-0009-00000001361-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/5990e772bb79/cureus-0009-00000001361-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/360f3662a93b/cureus-0009-00000001361-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/aa9f43ea8f92/cureus-0009-00000001361-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/f6ee125e85e2/cureus-0009-00000001361-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/8e4d1c59c195/cureus-0009-00000001361-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/2090e14e2578/cureus-0009-00000001361-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab0/5510969/0dad5c2281c4/cureus-0009-00000001361-i07.jpg

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