Mazocco Letícia, Chagas Patrícia
Universidade Federal de Santa Maria (UFSM), Programa de Pós-Graduação em Gerontologia, Santa Maria, RS, Brazil.
Universidade Federal de Santa Maria (UFSM), Programa de Pós-Graduação em Gerontologia, Santa Maria, RS, Brazil; Universidade Federal de Santa Maria (UFSM), Departamento de Alimentos e Nutricão, Palmeira das Missões, RS, Brazil.
Rev Bras Reumatol Engl Ed. 2017 Jul-Aug;57(4):299-305. doi: 10.1016/j.rbre.2016.10.002. Epub 2016 Nov 9.
To investigate the association between body mass index (BMI) and bone mineral density (BMD) in postmenopausal women.
Observational study with postmenopausal women who underwent bone densitometry in Palmeira das Missões - RS. Sociodemographic data, risk for osteoporosis and food intake were assessed through a specific form. BMI was calculated according to WHO criteria. The assessment of BMD was performed by dual-energy X-ray absorptiometry (DXA) and classified according to WHO. Statistical analysis was performed using prevalence ratios (PR) and their respective 95% confidence intervals for the factors studied. Variables associated with p<0.20 with the different outcomes (osteopenia and osteoporosis) were included in a Poisson regression model with robust variance to adjust for potential confounding factors. A 5% significance level was considered.
393 postmenopausal women with a mean age of 59.6±8.2 years participated. After the adjustments, the normal weight women had 1.2 times the prevalence of osteopenia of obese women (PR=1.2; CI 95% 1.3-1.5). Considering osteoporosis, the PR of euthophic women was twice the PR of obese women (PR=2; CI 95% 1.4-2.9) and was 1.7 times greater for overweight group compared to obese category (PR=1.7; CI 95% 1.2-2.5).
Obese women had lower prevalence of osteopenia compared with normal weight subjects and also with lower prevalence of osteoporosis as compared to normal- and overweight women.
探讨绝经后女性体重指数(BMI)与骨密度(BMD)之间的关联。
对在南里奥格兰德州帕尔梅ira das Missões接受骨密度测定的绝经后女性进行观察性研究。通过特定表格评估社会人口统计学数据、骨质疏松风险和食物摄入量。根据世界卫生组织标准计算BMI。采用双能X线吸收法(DXA)进行骨密度评估,并根据世界卫生组织标准进行分类。使用患病率比(PR)及其各自的95%置信区间对研究因素进行统计分析。将与不同结局(骨质减少和骨质疏松)p<0.20相关的变量纳入泊松回归模型,并采用稳健方差来调整潜在的混杂因素。显著性水平设定为5%。
393名平均年龄为59.6±8.2岁的绝经后女性参与了研究。调整后,正常体重女性骨质减少的患病率是肥胖女性的1.2倍(PR=1.2;95%置信区间1.3 - 1.5)。就骨质疏松而言,体重正常女性的PR是肥胖女性的两倍(PR=2;95%置信区间1.4 - 2.9),超重组与肥胖组相比PR高1.7倍(PR=1.7;95%置信区间1.2 - 2.5)。
与正常体重受试者相比,肥胖女性骨质减少的患病率较低,与正常体重和超重女性相比,肥胖女性患骨质疏松的患病率也较低。