Li Feng, He Zhisheng, Ye Yang
State Key Laboratory of Drug Research, and Natural Products Chemistry Department, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Acta Pharm Sin B. 2017 Jul;7(4):527-531. doi: 10.1016/j.apsb.2017.04.005. Epub 2017 Jun 21.
A new semi-quinonechalcone -glycoside isocartormin along with cartormin and safflomin C were isolated from the water extract of L. The structure of isocartormin was determined by extensive analysis of HR-MS, 1D- and 2D NMR data, and by comparison with those of cartormin reported previously by our group. Isocartormin was identified as a diastereoisomer of cartormin with a reverse configuration at C-18.
从L的水提取物中分离出一种新的半醌查耳酮糖苷异卡托明以及卡托明和藏红花素C。通过对高分辨质谱、一维和二维核磁共振数据的广泛分析,并与我们小组之前报道的卡托明的数据进行比较,确定了异卡托明的结构。异卡托明被鉴定为卡托明的非对映异构体,在C-18处具有相反的构型。