Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Center of Experimental and Applied Cutaneous Physiology (CCP), Department of Dermatology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Bioactive Food GmbH, Am Ihlsee 36a, 23795 Bad Segeberg, Germany.
Nutrients. 2017 Jul 19;9(7):775. doi: 10.3390/nu9070775.
Two differently designed, spatially resolved reflectance spectroscopy-based scanners and two-photon tomography were used for noninvasive in vivo determination of cutaneous carotenoids, and collagen I/elastin aging index of dermis, respectively, in the skin of 29 healthy female volunteers between 40 and 56 years of age. The volunteers received a supplement in the form of a carotenoid-rich natural curly kale extract containing 1650 µg of carotenoids in total (three capsules of 550 µg), once a day. Measurements were taken before, after 5 months and after 10 months of daily supplementation. The results showed significantly increased values for the cutaneous carotenoids and the collagen I/elastin aging index of dermis 5 and 10 months after the beginning of the study. The obtained results show that a natural carotenoid-rich extract could prevent the aging-related collagen I degradation in the dermis and improve the extracellular matrix.
两种不同设计的、基于空间分辨反射光谱的扫描仪和双光子断层扫描被用于分别无创地在 29 名 40 至 56 岁健康女性志愿者的皮肤中测定皮肤类胡萝卜素和真皮层胶原蛋白 I/弹性蛋白老化指数。志愿者每天以富含类胡萝卜素的天然卷曲羽衣甘蓝提取物的形式补充 1650µg 的类胡萝卜素（每天三粒，每粒 550µg）。在开始研究之前、5 个月后和 10 个月后进行测量。结果表明，在研究开始后的 5 个月和 10 个月后，皮肤类胡萝卜素和真皮层胶原蛋白 I/弹性蛋白老化指数的值显著增加。研究结果表明，天然富含类胡萝卜素的提取物可以防止真皮层与年龄相关的胶原蛋白 I 降解，改善细胞外基质。
