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含茶树油漱口水抗菌与抗炎作用的比较研究

A comparative study of antibacterial and anti-inflammatory effects of mouthrinse containing tea tree oil.

作者信息

Salvatori C, Barchi L, Guzzo F, Gargari M

机构信息

Department of Dentistry "Fra G.B. Orsenigo - Ospedale San Pietro F.B.F.", Rome, Italy.

Private Practice, Rome, Italy.

出版信息

Oral Implantol (Rome). 2017 Apr 10;10(1):59-70. doi: 10.11138/orl/2017.10.1.059. eCollection 2017 Jan-Mar.

Abstract

UNLABELLED

The study evaluated the antibacterial and anti-inflammatory efficacy, domiciliary oral hygiene, of a mouthrinse containing Tea Tree Oil (TTO) comparing it with two mouthrinses containing chlorhexidine 0,12% respectively and essential oils, and a placebo.

MATERIALS AND METHODS

A pilot study, randomized 4 × 4, controlled, cross-over, double-blind. 16 subjects with gingivitis (7 males and 9 females) aged 21-37 years, were randomly divided into four groups based on mouthwash that had to be used for domiciliary oral hygiene: mouthwash with essential oils, mouthwash with chlorhexidine 0,12 %, mouthwash containig tea tree oil and mouthwash placebo. Clinical evaluation was performed by: Full Mouth Plaque Score (FMPS), Full Mouth Bleeding Score (FMBS), Gingival Index (GI), discolorations, language examination and alteration of taste. The data were recorded before and 2 weeks after treatment.

RESULTS

Statistical analysis shows that treatments with tea tree oil, essential oils and chlorhexidine are effective. Comparing treatments should be noted that the tea tree oil gives a greater improvement in the GI and FMBS, while it is the least effective in the control of bacterial plaque.

CONCLUSION

Although further studies are needed, the anti-inflammatory properties of the mouthwash made from TTO would seem to be a valuable non-toxic adjunct in the management of gingivitis.

摘要

未标注

本研究评估了含茶树油(TTO)漱口水的抗菌和抗炎功效、家庭口腔卫生情况,并将其与两种分别含0.12%氯己定和精油的漱口水以及一种安慰剂进行比较。

材料与方法

一项初步研究,采用4×4随机、对照、交叉、双盲设计。16名年龄在21 - 37岁的牙龈炎患者(7名男性和9名女性),根据用于家庭口腔卫生的漱口水被随机分为四组:含精油漱口水、含0.12%氯己定漱口水、含茶树油漱口水和安慰剂漱口水。通过以下方式进行临床评估:全口菌斑评分(FMPS)、全口出血评分(FMBS)、牙龈指数(GI)、变色情况、语言检查和味觉改变。在治疗前和治疗2周后记录数据。

结果

统计分析表明,使用茶树油、精油和氯己定进行治疗均有效。比较各治疗方法时应注意,茶树油在改善牙龈指数和全口出血评分方面效果更佳,而在控制牙菌斑方面效果最差。

结论

尽管需要进一步研究,但由茶树油制成的漱口水的抗炎特性似乎是治疗牙龈炎的一种有价值的无毒辅助方法。

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本文引用的文献

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EXPERIMENTAL GINGIVITIS IN MAN.人类实验性牙龈炎
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