Lang Patrick, Karram Mickey
aThe Christ Hospital bThe Christ Hospital, Division of Urogynecology, Cincinnati, Ohio, USA.
Curr Opin Obstet Gynecol. 2017 Oct;29(5):354-358. doi: 10.1097/GCO.0000000000000399.
The purpose of this review is to discuss the available energy sources used in the vaginal canal that are currently being promoted for certain pelvic floor conditions and explore the body of peer-reviewed literature supporting their use.
The majority of research has focused on the use of fractional CO2 laser treatment for genitourinary syndrome of menopause (GSM). Most of these studies are nonrandomized prospective studies, but their data consistently shows an improvement in symptoms without significant side effects.
Vaginal laser treatment for GSM is of particular interest to gynecologists as it provides patients with a history of estrogen receptor positive breast cancer, thromboembolic event, or other contraindication to hormone therapy, an effective treatment option. Currently, we are in the early stages of scientific investigation into the use of lasers in the treatment of pelvic floor dysfunction, but the emerging data is encouraging. The existing data is limited to mostly observational studies with additional quality randomized controlled trials and sham studies needed to ensure that physicians are providing the optimum evidence-based treatments to their patients. At the present time there is insufficient data to promote these therapies for stress incontinence, vaginal tightening, or other pelvic floor abnormalities.
本综述旨在讨论目前针对某些盆底疾病所推广的阴道内使用的能量来源,并探讨支持其应用的同行评审文献。
大多数研究集中于使用分次二氧化碳激光治疗绝经后泌尿生殖综合征(GSM)。这些研究大多为非随机前瞻性研究,但其数据一致显示症状有所改善且无明显副作用。
对于有雌激素受体阳性乳腺癌病史、血栓栓塞事件或激素治疗其他禁忌症的患者,阴道激光治疗GSM为妇科医生提供了一种有效的治疗选择,因而备受关注。目前,我们正处于激光治疗盆底功能障碍的科学研究早期阶段,但新出现的数据令人鼓舞。现有数据大多限于观察性研究,还需要更多高质量的随机对照试验和假对照研究,以确保医生为患者提供基于最佳证据的治疗。目前,尚无足够数据支持将这些疗法用于治疗压力性尿失禁、阴道紧缩或其他盆底异常情况。