Department of Mechanical and Aerospace Engineering, The George Washington University, 800 22nd Street, NW, Washington DC 20052, United States of America.
Nanotechnology. 2017 Sep 20;28(38):382001. doi: 10.1088/1361-6528/aa8351. Epub 2017 Aug 1.
The field of tissue engineering is advancing steadily, partly due to advancements in rapid prototyping technology. Even with increasing focus, successful complex tissue regeneration of vascularized bone, cartilage and the osteochondral interface remains largely illusive. This review examines current three-dimensional printing techniques and their application towards bone, cartilage and osteochondral regeneration. The importance of, and benefit to, nanomaterial integration is also highlighted with recent published examples. Early-stage successes and challenges of recent studies are discussed, with an outlook to future research in the related areas.
组织工程领域正在稳步发展，部分原因是快速原型制造技术的进步。尽管关注度不断提高，但成功的血管化骨、软骨和骨软骨界面的复杂组织再生在很大程度上仍然难以实现。本文综述了当前的三维打印技术及其在骨、软骨和骨软骨再生中的应用。还强调了纳米材料集成的重要性和益处，并列举了最近发表的一些实例。讨论了近期研究的早期成功和挑战，并展望了相关领域的未来研究。
