Abdulla Maheeba, Al Saeed Mahmood, Fardan Rawdha Hameed, Alalwan Hawra Faisal, Ali Almosawi Zahra S, Almahroos Amal Fuad, Al Qamish Jehad
Department of Internal Medicine, Salmaniya Medical Complex, Manama, Bahrain.
Ibn Al Nafees Hospital, Manama, Bahrain.
Clin Exp Gastroenterol. 2017 Jul 14;10:133-145. doi: 10.2147/CEG.S127909. eCollection 2017.
The number of newly diagnosed inflammatory bowel disease (IBD) cases such as ulcerative colitis (UC), Crohn's disease (CD), and indeterminate colitis (IC) is rapidly increasing in Gulf countries and Saudi Arabia. The aim of this study was to investigate the incidence and prevalence of IBD in patients who have attended the Salmaniya Medical Complex, Bahrain, between the years 1984 and 2014.
All patients who had attended the Salmaniya Medical Complex, Bahrain, and had been diagnosed with UC, CD, or IC, between the years 1984 and 2014, were included in the analysis. Data collected were: patient demographics, symptoms, clinical signs, complications, surgical interventions, extent of disease, endoscopic findings, histopathology, and lab measurements.
A total of 187 cases were included; 61 had CD, 123 had UC, and a further 3 cases presented with IC. A clear increase in the incidence and prevalence of IBD can be seen in this cohort. The prevalence of IBD was calculated to be 26.25/10 cases. The average number of IBD cases increased from 3 cases (average for the years 1984-2001) to 12 cases (average for the years 2002-2014). A number of factors correlate positively or negatively with CD and UC. In the current study, a link between gastrointestinal complications in CD cases and the use of steroids as a treatment was noted (-value -0.02). Age also had a significant influence on the need for surgery in CD cases (-value -0.04), and a family history of UC was statistically linked to surgical intervention (-value -0.05).
IBD can no longer be considered a rare disease in Bahrain. The incidence of both UC and CD is steadily increasing. There is a need for increasing awareness of the Bahraini public to IBD in order for proper medical care to be given.
在海湾国家和沙特阿拉伯，新诊断出的炎症性肠病（IBD）病例数量，如溃疡性结肠炎（UC）、克罗恩病（CD）和未定型结肠炎（IC）正在迅速增加。本研究的目的是调查1984年至2014年间在巴林萨尔曼尼亚医疗中心就诊的患者中IBD的发病率和患病率。
纳入分析的患者为1984年至2014年间在巴林萨尔曼尼亚医疗中心就诊且被诊断为UC、CD或IC的所有患者。收集的数据包括：患者人口统计学信息、症状、临床体征、并发症、手术干预、疾病范围、内镜检查结果、组织病理学以及实验室检测结果。
共纳入187例病例；其中61例为CD，123例为UC，另有3例为IC。在这一队列中可明显看出IBD的发病率和患病率有所增加。IBD的患病率经计算为26.25/10万例。IBD病例的平均数量从3例（1984 - 2001年的平均值）增加到12例（2002 - 2014年的平均值）。一些因素与CD和UC呈正相关或负相关。在本研究中，注意到CD病例的胃肠道并发症与使用类固醇作为治疗之间存在关联（P值 - 0.02）。年龄对CD病例的手术需求也有显著影响（P值 - 0.04），UC家族史与手术干预在统计学上相关（P值 - 0.05）。
在巴林，IBD不能再被视为罕见疾病。UC和CD的发病率都在稳步上升。需要提高巴林公众对IBD的认识，以便提供适当的医疗护理。
