Englund Marianne, Persson Jan, Bergström Ingrid
a Department of surgery at Danderyds Hospital , Stockholm , Sweden.
b Department of Anaesthesia and Intensive Care , Karolinska University Hospital Stockholm , Stockholm , Sweden.
Int J Circumpolar Health. 2017;76(1):1340547. doi: 10.1080/22423982.2017.1340547.
Vitamin D deficiency is common among immigrants in the Nordic region. It may lead to osteomalacia with severe musculoskeletal pain. There are reports that vitamin D deficiency without osteomalacia may lead to pain but little is known of the effect of treatment.
To investigate whether a moderate dose of cholecalciferol and calcium improves strength and pain in a group of vitamin D deficient women.
Twentyfive immigrant women with vitamin D deficiency diagnosed during pregnancy were treated postpartum with a daily dose of 1,600 IU cholecalciferol and 1,000 mg of calcium. They were examined at the start of treatment and again after 3 months of treatement and the results were statistically compared.
Southern parts of Stockholm.
Serum 25-hydroyvitamin D (25(OH)D), serum-parathyroid hormone (PTH), pain measured by a visual analogue scale (VAS), musculoskeletal strength by performance on a chair stand test (seconds), and bone tenderness by pressure algometer (kilo-Pascal).
Following the treatment, the 21 women attending had lowered cm in VAS, improved musculoskeletal strength, - and 25(OH)D levels were normalized.
A moderate dose of vitamin D normalized l vitamin D levels, improved muscular strength and reduced pain in this group of vitamin D deficient immigrant women.
维生素D缺乏在北欧地区的移民中很常见。它可能导致骨软化症并伴有严重的肌肉骨骼疼痛。有报道称，无骨软化症的维生素D缺乏可能导致疼痛，但关于治疗效果知之甚少。
研究中等剂量的胆钙化醇和钙是否能改善一组维生素D缺乏女性的力量和疼痛状况。
对25名在孕期被诊断为维生素D缺乏的移民女性在产后进行治疗，每日给予1600国际单位胆钙化醇和1000毫克钙。在治疗开始时以及治疗3个月后对她们进行检查，并对结果进行统计学比较。
斯德哥尔摩南部地区。
血清25-羟维生素D（25(OH)D）、血清甲状旁腺激素（PTH）、通过视觉模拟量表（VAS）测量的疼痛、通过椅子站立试验表现（秒）测量的肌肉骨骼力量以及通过压力痛觉计（千帕斯卡）测量的骨压痛。
治疗后，参与研究的21名女性的VAS评分降低，肌肉骨骼力量得到改善，且25(OH)D水平恢复正常。
中等剂量的维生素D使该组维生素D缺乏的移民女性的维生素D水平恢复正常，增强了肌肉力量并减轻了疼痛。
